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| Autologous neutralising antibody specificities in HIV-1 subtype C: characterising the C3V4 region and defining the mechanisms of escape | |
| Bhiman;Jinal Nomathemba | |
| 出版年 | 2014 |
| 英文摘要 | Most new HIV-1 infections world-wide are caused by subtype C viruses. The C3V4 region, including the alpha2-helix and V4 loop, has been identified as a major target for autologous neutralising antibodies in subtype C infections. Factors associated with the immunogenicity of this region, and the mechanisms of escape from anti-C3V4 responses have not been described, although charge changes in the alpha2-helix have been proposed to mediate neutralisation escape. |
| 英文关键词 | HIV-1 Infections--immunology |
| 语种 | 英语 |
| URL | http://hdl.handle.net10539/13796 |
| 资源类型 | 学位论文 |
| 条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/248866 |
| 推荐引用方式 GB/T 7714 | Bhiman;Jinal Nomathemba. Autologous neutralising antibody specificities in HIV-1 subtype C: characterising the C3V4 region and defining the mechanisms of escape[D],2014. |
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