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Deficient attentional and inhibitory control with associated neurophysiologic abnormalities of frontal area and anterior cingulate cortex in ASD children. CUHK electronic theses & dissertations collection
[null]
出版年2010
英文摘要Conclusion: The results suggest that ASD children have deficits in attentional and inhibitory control. Frontal dysfunction and weak ACC engagement in ASD were supported as the underlying neuronal inefficiency. Methods: 20 children with high-functioning ASD [Mean Age (SD): 10.75 years old (2.07 years); Mean IQ (SD): 101.4 (16.8)] and age- and IQ-matched normal children (NC) [Mean Age (SD): 9.80 years old (1.88 years); Mean IQ (SD): 110.7(17.8)] were investigated electrophysiologically during performance of a visual Go/NoGo task. An electrophysiological source localization method was employed to further analyze the data. Several different neurospsychological tests were also performed to provide behavioral measures on attention and inhibition. Objectives: To investigate neurophysiologic abnormalities in frontal and anterior cingulate cortex underlying attentional and inhibitory control in children with Autism Spectrum Disorder (ASD). Results: ASD children showed a significantly task-related lower frontal theta activity. This effect was associated with a significantly reduced activation of the anterior cingulate cortex (ACC). Both groups also differ significantly regarding the behavioral aspects of attention and inhibition. Leung, Shuk Yin Connie. "November 2009." Adviser: Chan Sue-Yin Agnes. Source: Dissertation Abstracts International, Volume: 72-01, Section: B, page: . Thesis (Ph.D.)--Chinese University of Hong Kong, 2010. Includes bibliographical references (leaves 65-85). Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. Abstracts also in Chinese.
英文关键词Autism spectrum disorders in children Neurophysiology Child Development Disorders Pervasive Gyrus Cinguli--pathology Neurophysiology
语种英语
URLhttp://library.cuhk.edu.hk/record=b6074826
资源类型学位论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/245114
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GB/T 7714
[null]. Deficient attentional and inhibitory control with associated neurophysiologic abnormalities of frontal area and anterior cingulate cortex in ASD children. CUHK electronic theses & dissertations collection[D],2010.
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