干旱区生态环境知识资源中心(Arid): 塔中栽培荒漠肉苁蓉中4个新的顺式苯乙醇苷类成分

Arid

	塔中栽培荒漠肉苁蓉中4个新的顺式苯乙醇苷类成分
其他题名	Four new cis-phenylethanoid glycosides from stems of Cistanche deserticola cultured in Tarim desert
	南泽东 1; 任华忠 1; 赵明波 2; 姜勇 2; 屠鹏飞 2
来源期刊	中国中药杂志
ISSN	1001-5302
出版年	2018
卷号	43 期号:6 页码:1169-1174
中文摘要	对新疆塔中栽培荒漠肉苁蓉Cistanche deserticola干燥肉质茎的化学成分进行研究。采用正相硅胶、凝胶Sephadex LH-20、MCI、ODS以及半制备高效液相色谱等方法进行分离纯化,运用NMR,MS等波谱方法以及结合文献数据对分离得到的化合物进行结构鉴定。从塔中栽培荒漠肉苁蓉干燥肉质茎85%乙醇提取物中分离得到4个化合物,其结构鉴定为顺式管花苷B (1)、顺式肉苁蓉苷K (2)、顺式肉苁蓉苷J (3)、顺式异肉苁蓉苷C (4)。化合物1~4为新的顺式苯乙醇苷类化合物,该文为首次报道4个新化合物的~1H-NMR和~(13)C-NMR波谱数据,为全面分析本种栽培品的化学成分提供了一定的科学数据。
英文摘要	In order to clarify the chemical constituents of Cistanche deserticola cultured in Tarim desert, a systematically phytochemical investigation was carried out. The chemical constituents were isolated by column chromatography, such as silica gel, Sephadex LH-20, MCI gel, ODS and semi-preparative HPLC, and their structures were determined on the basis of MS, NMR spectroscopic analysis, and comparison with literature data. Four compounds were isolated from the 85% ethanol extract of the stems of C. cultured in Tarim desert. Their structures were identified as cis-tubuloside (1), cis-cistanoside (2), cis-cistanoside J (3), and cis-isocistanoside C (4). Compounds 1-4 were four new cis-phenylethanoid glycosides. Herein, we firstly report the ~1H, ~(13)C-NMR data of the new compounds (1-4) for the first time. This study will provide the scientific evidence for comprehensively analyzing the chemical constituents of C. deserticola cultured in Tarim desert.
中文关键词	荒漠肉苁蓉 ; 肉苁蓉属 ; 顺式苯乙醇苷 ; 结构鉴定
英文关键词	Cistanche deserticola Cistanche cis-phenylethanoid glycoside structure elucidation
语种	中文
国家	中国
收录类别	CSCD
WOS类目	MEDICINE GENERAL INTERNAL
WOS研究方向	General & Internal Medicine
CSCD记录号	CSCD:6226137
来源机构	北京大学
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/238873
作者单位	1.乐山职业技术学院, 乐山, 四川 614000, 中国; 2.北京大学药学院, 天然药物及仿生药物国家重点实验室, 北京 100191, 中国
推荐引用方式 GB/T 7714	南泽东,任华忠,赵明波,等. 塔中栽培荒漠肉苁蓉中4个新的顺式苯乙醇苷类成分[J]. 北京大学,2018,43(6):1169-1174.
APA	南泽东,任华忠,赵明波,姜勇,&屠鹏飞.(2018).塔中栽培荒漠肉苁蓉中4个新的顺式苯乙醇苷类成分.中国中药杂志,43(6),1169-1174.
MLA	南泽东,et al."塔中栽培荒漠肉苁蓉中4个新的顺式苯乙醇苷类成分".中国中药杂志 43.6(2018):1169-1174.