干旱区生态环境知识资源中心(Arid): 极干旱区大气PM

Arid

	极干旱区大气PM_(2.5)对质粒DNA的氧化性损伤研究
其他题名	Analysis of Oxidative Capacity of PM_(2.5)in Arid Area
	图尔贡·艾尔肯 1; 迪丽努尔·塔力甫 1; 邵龙义 2; 买丽克扎提·买合木提 1; 亚力昆江·吐尔逊 1; 阿布力克木·阿布力孜 1
来源期刊	生态环境学报
ISSN	1674-5906
出版年	2018
卷号	27 期号:4 页码:730-735
中文摘要	近年来和田经济迅速发展及城市人口快速增长,汽车尾气、工业废气等各类污染物的城区排放量也在不断增加,加重了和田市大气污染.为评估和田市城区风速、沙尘天气对大气PM_(2.5)毒性的影响,于2014年1月、4月、7月、1011月采集大气PM_(2.5)样品,应用质粒DNA评价法研究其PM_(2.5)的氧化性损伤能力.结果表明,采样期间,和田市城区大气PM_(2.5)质量浓度的变化范围为70~2 489 mug·m~(-3),PM_(2.5)质量浓度有随风速增大而增大的趋势.应用TD30(造成30% DNA损伤率所需的颗粒物剂量,mug·mL~(-1))值指示颗粒物氧化性损伤能力,结果表明,TD30越高,颗粒物氧化性损伤能力越弱,全样和水溶部分TD30值的变化范围分别为444~27 480 mug·mL~(-1)和481~20 434 mug·mL~(-1);不论是全样还是水溶部分,其对质粒DNA的氧化性损伤均表现出随风速减小而增大的变化趋势;沙尘和非沙尘期间全样TD30的平均值分别为9 464 mug·mL~(-1)和8 008 mug·mL~(-1),而水溶部分分别为5 494 mug·mL~(-1)和7 822 mug·mL~(-1),即沙尘期间采集的颗粒物对体外DNA的氧化性损伤小于非沙尘期间采集的样品,且非沙尘期间采集的样品的全样损伤大于相应的水溶部分样,而沙尘状况下体外DNA的氧化性损伤可能主要来源于水溶成分.全样和水溶部分的TD30平均值与PM_(2.5)平均质量浓度之间存在明显的正相关趋势,说明颗粒物的质量浓度对DNA氧化损伤起着一定的作用.
英文摘要	In recent years, the rapid economic development of Hotan City and rapid population growth caused increase in air pollution from vehicles and industry. In order to evaluate the effect of dust whether on the toxicity of PM_(2.5)of urban area, the PM_(2.5) samples were collected from January to December 2014 to analyze the oxidative capacity of the PM_(2.5)particles by plasmid scission assay. The result showed that, the mass concentration of PM_(2.5)ranged from 70 to 2 489 mug·m~(-3) and which had been increased with the wind speed. The TD30 (toxic dose of PM causing 30% of plasmid DNA damage, mug·mL~(-1)) was used to indicate the oxidative capacity. The TD30 values of whole and water soluble fraction of PM_(2.5)samples were 444~27 480 mug·mL~(-1) and 481~20 434 mug·mL~(-1), respectively. Both of the whole and water soluble fractions indicated that the lower the wind speed caused the higher the oxidative damage to plasmid DNA. During sand and non-sand period, the average TD30 values of whole and water soluble fraction were 9 464 mug·mL~(-1) and 8 008 mug·mL~(-1) and water soluble were 5 494 mug·mL~(-1) and 7 822 mug·mL~(-1) respectively. The oxidative damage of whole particles were higher than their corresponding water-soluble fractions during the non-dust storm period, on contrast, the toxicity of the particles was mainly sourced from their water soluble fraction during the dust storm period. Both of the TD30 in whole and water soluble fraction positively correlated with PM_(2.5)mass concentration indicated that the mass concentration of PM_(2.5)played an important role in oxidative damage.
中文关键词	氧化性损伤 ; 质粒DNA评价法 ; 和田市城区
英文关键词	PM_(2.5) PM_(2.5) oxidative damage plasmid DNA Hotan City
语种	中文
国家	中国
收录类别	CSCD
WOS类目	ENVIRONMENTAL SCIENCES
WOS研究方向	Environmental Sciences & Ecology
CSCD记录号	CSCD:6236530
来源机构	新疆大学
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/238072
作者单位	1.新疆大学, 煤炭清洁转化与化工过程新疆自治区重点实验室, 乌鲁木齐, 新疆 830046, 中国; 2.中国矿业大学资源与地球科学系(北京), 煤炭资源与安全开采国家重点实验室, 北京 100083, 中国
推荐引用方式 GB/T 7714	图尔贡·艾尔肯,迪丽努尔·塔力甫,邵龙义,等. 极干旱区大气PM_(2.5)对质粒DNA的氧化性损伤研究[J]. 新疆大学,2018,27(4):730-735.
APA	图尔贡·艾尔肯,迪丽努尔·塔力甫,邵龙义,买丽克扎提·买合木提,亚力昆江·吐尔逊,&阿布力克木·阿布力孜.(2018).极干旱区大气PM_(2.5)对质粒DNA的氧化性损伤研究.生态环境学报,27(4),730-735.
MLA	图尔贡·艾尔肯,et al."极干旱区大气PM_(2.5)对质粒DNA的氧化性损伤研究".生态环境学报 27.4(2018):730-735.