干旱区生态环境知识资源中心(Arid): PTV-GC-MS/MS及UPLC-MS/MS测定水产品中多种农兽药残留

Arid

	PTV-GC-MS/MS及UPLC-MS/MS测定水产品中多种农兽药残留
其他题名	Multiresidue determination of pesticide and veterinary drugs in aquatic products by PTV-GC-MS /MS and UPLC-MS /MS
	黄子敬 1; 陈孟君 1; 符靖雯 1; 罗汉金 2
来源期刊	化学研究与应用
ISSN	1004-1656
出版年	2018
卷号	30 期号:8 页码:1376-1387
中文摘要	建立了程序升温进样-气相色谱-三重四级杆串联质谱仪(PTV-GC-MS/MS)检测水产品中42种农药残留和超高效液相色谱-串联质谱(UPLC-MS/MS)测定水产品中28种兽药残留的分析方法。样品经2%甲酸乙腈提取,Oasis PRiME HLB固相萃取柱净化后,通过优化色谱参数和质谱参数,提高灵敏度、降低基质及农药重叠峰干扰,采用多反应监测(MRM)模式,以保留时间和离子对进行定性,峰面积定量。42种农药和28种兽药线性关系良好,相关系数大于0.99,在3个添加水平下的平均回收率为62.4%~ 111.3%,相对标准偏差为1.1%~ 11.1%,检出限(LOD)为0.0002~ 0.0079mg·kg~(-1),定量限(LOQ)为0.0007~ 0.0261 mg·kg~(-1)。该法具有操作简单、快速、节省溶剂、准确灵敏等特点,适用于水产品中农兽药多残留的快速筛查。
英文摘要	A temperature-programmed triple quadrupole gas chromatography-mass spectrometer(PTV-GC-MS /MS) method was established for the determination of 42 pesticide residues and also a ultra high performance liquid chromatography tandem mass spectrometry(UPLC-MS /MS) method for the 28 veterinary drug residues in aquatic products.The samples were extracted by 2%formic acid acetonitrile,purified by Oasis PRiME HLB solid phase extraction column.The sensitivity was increased and the interference of overlapping peaks and pesticide peaks are reduced by optimizing the chromatographic and mass spectral parameters.Multiple reaction monitoring(MRM) were adopted, the retention time and the ion pairs were used for qualitative determination, the peak areas were used for quantitative determination.The linear relationship between 42 pesticides and 28 veterinary drugs was good, the correlation coefficient was above 0.99, the average recovery was 62.4%~ 111.3%and the relative standard deviation was 1.1%~ 11.1%at 3 addition levels. The limits of detection(LOD) were in the range of 0.0002 ~ 0.0079mg·kg~(-1),and the limit of quantification (LOQ) was 0.0007~ 0.0261 mg·kg~(-1). The method is simple, fast, solvent-saving,accurate and sensitive characteristics, suitable for rapid screening of pesticides and pesticides residues in aquatic products.
中文关键词	水产品 ; 农药残留 ; 兽药残留 ; 程序升温汽化(PTV)
英文关键词	GC-MS /MS UPLC-MS /MS aquatic product pesticide residue veterinary drug residue programmed temperature vaporization(PTV) GC-MS /MS UPLC-MS /MS
语种	中文
国家	中国
收录类别	CSCD
WOS类目	CHEMISTRY ANALYTICAL
WOS研究方向	Chemistry
CSCD记录号	CSCD:6319125
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/237835
作者单位	1.惠州市农产品质量安全监督检测中心, 惠州, 广东 516008, 中国; 2.华南理工大学环境与能源学院, 广州, 广东 510006, 中国
推荐引用方式 GB/T 7714	黄子敬,陈孟君,符靖雯,等. PTV-GC-MS/MS及UPLC-MS/MS测定水产品中多种农兽药残留[J],2018,30(8):1376-1387.
APA	黄子敬,陈孟君,符靖雯,&罗汉金.(2018).PTV-GC-MS/MS及UPLC-MS/MS测定水产品中多种农兽药残留.化学研究与应用,30(8),1376-1387.
MLA	黄子敬,et al."PTV-GC-MS/MS及UPLC-MS/MS测定水产品中多种农兽药残留".化学研究与应用 30.8(2018):1376-1387.