干旱区生态环境知识资源中心(Arid): 牛津急性疾病严重程度评分对重症患者病情评估的价值:单中心470例病例分析

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	牛津急性疾病严重程度评分对重症患者病情评估的价值:单中心470例病例分析
其他题名	The study of the value of Oxford Acute Severity of Illness Score in assessing the severity of critical illness patients: a single-center analysis of 470 cases
	张牧城; 汪正光; 洪曦菲; 郑绍鹏; 方向群; 谢利德
来源期刊	中华急诊医学杂志
ISSN	1671-0282
出版年	2017
卷号	26 期号:2 页码:197-201
中文摘要	目的探讨牛津急性疾病严重程度评分(Oxford acute severity of illness score, OASIS)在重症患者病情评估和预后判断中的价值。方法选择我科2012年8月至2014年7月收治的重症患者为研究对象进行回顾性研究,分别计算每一位患者牛津急性疾病严重程度评分和APACHE Ⅲ评分,然后进行统计学处理与分析。结果共470例患者被纳入本研究,其中男321例,女149例,年龄(18~97)岁,(5918)岁,存活347例,死亡123例,病死率26.170%。牛津急性疾病严重程度评分ROC曲线下面积0.760 (95% CI: 0.712 ~ 0.808, P<0.01),评分30.5时Youden指数最大,为0.352。APACHE Ⅲ评分ROC曲线下面积0.844 (95%CI: 0.806~0.882, P<0.01),评分70.5分时Youden指数最大,为0.503。随牛津急性疾病严重程度评分的增加,患者的病死率逐渐上升,牛津急性疾病严重程度评分≥40分时,病死率在70%以上,Spearman双变量相关分析,r, =0.976, (P<0.01)。结论牛津急性疾病严重程度评分对重症患者病情评估与预后判断有较好的效果,相对APACHE Ⅲ评分更简单、依从性好。
英文摘要	Objective To explore the value of Oxford acute severity of illness score in evaluating the severity and prognosis of critical illness patients. Methods All adult patients admitted to the Department of Critical Care Medicine from August 2012 to July 2014 were retrospectively analyzed. The severity in survivors and non-survivors was evaluated by using Oxford acute severity of illness score and APACHE Ⅲscore, and then statistic analysis were performed. Results Of 470 patients, 321 (68.297%) were male, the range of age and (x s) age were 18 to 97 years and (59 18) years respectively, and 123 patients (26.170%) were in non-survivors group and 347 patients in survivors group. The area under the ROC of Oxford acute severity of illness score was 0.760 (95% CI: 0.712-0.808, P<0.001), and Youden index was biggest when Oxford acute severity of illness score was 30.5. The area under the ROC of APACHE Ⅲscore was 0.844 (95% CI: 0.806-0.882, P < 0.01), and Youden index was biggest when APACHE Ⅲscore was 70.5. Mortality was high (above 70%) as Oxford acute severity of illness score increased (> 40),and Spearman r was 0.976 (P <0.01). Conclusions Oxford Acute Severity of Illness Score was useful to evaluating the severity and prognosis of critical illness patients and it was easy in clinical practice.
中文关键词	牛津急性疾病严重程度评分 ; 急性生理学与慢性健康状况评分系统Ⅲ ; 重症患者 ; 病情 ; 预后 ; 价值
英文关键词	Oxford Acute Severity of Illness Score (OASIS) Acute physiology and chronic health evaluation (APACHE) Ⅲ score Critical care patients Severity Prognosis Value
语种	中文
国家	中国
收录类别	CSCD
WOS类目	MEDICINE GENERAL INTERNAL
WOS研究方向	General & Internal Medicine
CSCD记录号	CSCD:5910042
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/237213
作者单位	皖南医学院附属黄山市人民医院重症医学科, 黄山, 安徽 245000, 中国
推荐引用方式 GB/T 7714	张牧城,汪正光,洪曦菲,等. 牛津急性疾病严重程度评分对重症患者病情评估的价值:单中心470例病例分析[J],2017,26(2):197-201.
APA	张牧城,汪正光,洪曦菲,郑绍鹏,方向群,&谢利德.(2017).牛津急性疾病严重程度评分对重症患者病情评估的价值:单中心470例病例分析.中华急诊医学杂志,26(2),197-201.
MLA	张牧城,et al."牛津急性疾病严重程度评分对重症患者病情评估的价值:单中心470例病例分析".中华急诊医学杂志 26.2(2017):197-201.