干旱区生态环境知识资源中心(Arid): 固相萃取-液相色谱-串联质谱法测定食品包装材料中16种全氟烷基类化合物

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	固相萃取-液相色谱-串联质谱法测定食品包装材料中16种全氟烷基类化合物
其他题名	Determination of 16 perfluorinated alkyl substances in food packaging materials by solid phase extraction-liquid chromatography-tandem mass spectrometry
	何建丽 1; 彭涛 1; 谢洁 1; 胡雪艳 1; 常巧英 1; 陈辉 1; 范春林 1; 李存 2
来源期刊	色谱
ISSN	1000-8713
出版年	2016
卷号	34 期号:7 页码:710-714
中文摘要	建立了使用固相萃取-液相色谱-串联质谱(SPE-LC-MS/MS)同时检测食品包装材料中16种全氟烷基类化合物(PFAS)的方法。分别对样品前处理方法、质谱条件等进行了比较和优化,样品用甲醇超声提取,经Oasis WAX固相萃取小柱净化后,用Atlantis T3 C_(18)色谱柱分离,以乙腈和5 mmol/L乙酸铵溶液为流动相进行梯度洗脱,多反应监测(MRM)负离子模式扫描,同位素内标法和外标法结合定量。16种PFAS在0.5~20.0mug/L范围内线性关系良好,相关系数(r~2)均大于0.99。加标回收率为68.6%~109.2%,RSD为2.5%~18.1%(n=6)。检出限为0.2~0.5 mug/kg,定量限为0.5~1.0 mug/kg。该方法简便、快速、准确,可用于食品包装材料样品中PFAS的检测。
英文摘要	A method for the simultaneous determination of 16 perfluorinated alkyl substances (PFAS) in food packaging materials by solid phase extraction-liquid chromatography-tandem mass spectrometry (SPE-LC-MS/MS) was developed. Comparison and optimization of the sample pretreatment methods, mass spectrometry and other conditions were carried out. The samples were ultrasonically extracted with methanol, followed by clean-up using an Oasis WAX SPE column. The analytes were separated on a reversed phase Atlantis T3 C_(18) column and eluted gradiently with acetonitrile and 5 mmol/L ammonium acetate. The analytes were quantified using isotope internal standard and isotope external standard calibration curve method. The linear calibration curves were obtained in the range of 0.5-20.0mug/L with the linear relative coefficients more than 0.99. The recoveries were in the range of 68.6%-109.2% and the relative standard deviations (RSDs) were ranged from 2.5% to 18.1% (n=6). The limits of detection (LODs) and the limits of quantification (LOQs) for the PFAS were 0.2-0.5 mug/kg and 0.5-1.0 mug/kg, respectively. This method is simple, rapid, accurate and can be used in the determination of PFAS in food packaging materials.
中文关键词	液相色谱-串联质谱 ; 固相萃取 ; 全氟烷基类化合物 ; 包装材料
英文关键词	liquid chromatography-tandem mass spectrometry (LC-MS/MS) solid phase extraction (SPE) perfluorinated alkyl substances (PFAS) food packaging materials
语种	中文
国家	中国
收录类别	CSCD
WOS类目	CHEMISTRY ANALYTICAL
WOS研究方向	Chemistry
CSCD记录号	CSCD:5745103
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/234695
作者单位	1.中国检验检疫科学研究院, 北京 100176, 中国; 2.天津农学院动物科学与动物医学学院, 天津 300384, 中国
推荐引用方式 GB/T 7714	何建丽,彭涛,谢洁,等. 固相萃取-液相色谱-串联质谱法测定食品包装材料中16种全氟烷基类化合物[J],2016,34(7):710-714.
APA	何建丽.,彭涛.,谢洁.,胡雪艳.,常巧英.,...&李存.(2016).固相萃取-液相色谱-串联质谱法测定食品包装材料中16种全氟烷基类化合物.色谱,34(7),710-714.
MLA	何建丽,et al."固相萃取-液相色谱-串联质谱法测定食品包装材料中16种全氟烷基类化合物".色谱 34.7(2016):710-714.