干旱区生态环境知识资源中心(Arid): 超高效液相色谱- 串联质谱同步检测艾比湖中14种抗生素

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	超高效液相色谱- 串联质谱同步检测艾比湖中14种抗生素
其他题名	DETERMINATION OF FOURTEEN ANTIBIOTICS IN WATER OF AIBI LAKE BY UPLC-MS/MS
	王倩倩 1; 鲁建江 1; 刘江 1; 吕新明 2
来源期刊	环境工程
ISSN	1000-8942
出版年	2016
卷号	34 期号:12 页码:153-157
中文摘要	采用超高效液相色谱-串联质谱法(UPLC-MS /MS),建立了同时检测水样中三类共计14种抗生素的分析方法。水样经HLB小柱萃取富集后,用10%甲醇含0. 1%的甲酸溶液定容,以高效液相色谱-串联质谱对目标物进行分析。在最优实验条件下,14种抗生素的线性范围为1. 0 ~ 500 mug /L,相关系数均大于0. 99,方法的检出限为0. 30 ~ 1. 23 ng /L。将建立的方法应用于检测艾比湖湖水中14种抗生素的残留分析,结果表明: 14种抗生素中共检测出12种,其中氧氟沙星、洛美沙星、环丙沙星、土霉素的检出率为100%,洛美沙星的浓度最高。
英文摘要	A method was developed for the determination of forteen antibiotics in water by UPLC-MS /MS. In the acid condition, target compounds were enriched with oasis HLB column and purified with 10% menthol and 0. 1% formic acid. The analytes were eluted with methanol,and subsequently quantified by UPLC-MS /MS mode. Under the optimal conditions,the calibration curves of all 14 targets were linear in the range of 1. 0 ~ 500 mug /L with correlation coefficients more than 0. 99. The method detection limits varied between 0. 30 ~ 1. 13 ng /L. Results showed that 12 antibiotics were detected among 14 antibiotics. Four antibiotics were the most frequently detected compounds of 100% and the highest concentrations was lomeftoxgcin.
中文关键词	抗生素 ; 超高效液相色谱- 串联质谱 ; 艾比湖
英文关键词	antibiotics UPLC-MS /MS Aibi Lake
语种	中文
国家	中国
收录类别	CSCD
WOS类目	ENVIRONMENTAL SCIENCES
WOS研究方向	Environmental Sciences & Ecology
CSCD记录号	CSCD:5884737
来源机构	石河子大学
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/234491
作者单位	1.石河子大学化学化工学院, 新疆兵团化工绿色过程重点实验室, 石河子, 新疆 832003, 中国; 2.阿拉山口出入境检验检疫局, 阿拉山口, 新疆 833418, 中国
推荐引用方式 GB/T 7714	王倩倩,鲁建江,刘江,等. 超高效液相色谱- 串联质谱同步检测艾比湖中14种抗生素[J]. 石河子大学,2016,34(12):153-157.
APA	王倩倩,鲁建江,刘江,&吕新明.(2016).超高效液相色谱- 串联质谱同步检测艾比湖中14种抗生素.环境工程,34(12),153-157.
MLA	王倩倩,et al."超高效液相色谱- 串联质谱同步检测艾比湖中14种抗生素".环境工程 34.12(2016):153-157.