干旱区生态环境知识资源中心(Arid): 塔中栽培荒漠肉苁蓉中的木脂素类成分

Arid

	塔中栽培荒漠肉苁蓉中的木脂素类成分
其他题名	Lignans from stems of Cistanche deserticola cultured in Tarim desert
	南泽东; 赵明波; 姜勇; 屠鹏飞
来源期刊	中国中药杂志
ISSN	1001-5302
出版年	2015
卷号	40 期号:3 页码:463-468
中文摘要	对新疆塔中栽培荒漠肉苁蓉Cistanche deserticola干燥肉质茎的化学成分进行研究。采用多种色谱技术(正相硅胶、凝胶Sephadex LH-20,MCI,ODS以及半制备高效液相色谱等)进行分离纯化,运用NMR、MS等波谱方法以及结合文献数据对分离得到的化合物进行结构鉴定。结果从塔中栽培荒漠肉苁蓉干燥肉质茎85%乙醇提取物中分离得到11个木脂素类化合物,其结构分别鉴定为:(+)-丁香脂素-4-O-beta-D-吡喃葡萄糖苷(1),(+)-isoeucommin A(2),(+)-麦奥迪脂素-4-O-beta-D-吡喃葡萄糖苷(3),(+)-松脂素单甲基醚-beta-D-葡萄糖苷(4),落叶松脂醇-4-O-beta-D-葡萄糖苷(5),落叶松脂醇-4-O-beta-D-葡萄糖苷(6),conicaoside(7),dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside(8),dehydrodiconiferyl alcoholgamma-O-beta-D-glucoside(9),橙皮素A(10),阿拉善苷A(11)。其中化合物1,3~7,10,11为首次从该属植物中分离得到,化合物2,8,9为首次从该植物中分离得到。
英文摘要	In order to clarify the chemical constituents of Cistanche deserticola cultured in Tarim desert,a systematically phytochemical investigation was carried out. The chemical constituents were isolated by column chromatography,such as silica gel,Sephadex LH- 20,MCI gel,ODS and semi-preparative HPLC,and their structures were determined on the basis of MS,NMR spectroscopic analysis and /or comparison with literature data. Eleven lignans were isolated from the 85% ethanol extract of the stems of C. deserticola cultured in Tarim desert. Their structures were identified as (+ ) -syringaresinol-4’-O-beta-D-glucopyranoside (1) ,(+ ) -isoeucommin A (2) ,eucommin A (3) ,(+ ) -pinoresinol monomethylether beta-D-glucoside (4) ,lariciresinol 4’-O-beta-D-glucopyranoside (5) ,lariciresinol 4-O-beta-D-glucopyranoside (6) ,conicaoside (7) ,dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside (8) ,dehydrodiconiferyl alcohol gamma’-O-beta-D-glucoside (9) ,citrusin A (10) , and alaschanioside A (11) . Compounds 1,3-7,10 and 11 were isolated from this genus for the first time,and compounds 2,8 and 9 were obtained from this species for the first time.
中文关键词	荒漠肉苁蓉 ; 木脂素 ; 化学成分 ; 结构鉴定
英文关键词	Cistanche deserticola Lignans Chemical constituents Structure elucidation
语种	中文
国家	中国
收录类别	CSCD
WOS类目	MEDICINE GENERAL INTERNAL
WOS研究方向	General & Internal Medicine
CSCD记录号	CSCD:5460858
来源机构	北京大学
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/233836
作者单位	北京大学, 天然药物及仿生药物国家重点实验室, 北京 100191, 中国
推荐引用方式 GB/T 7714	南泽东,赵明波,姜勇,等. 塔中栽培荒漠肉苁蓉中的木脂素类成分[J]. 北京大学,2015,40(3):463-468.
APA	南泽东,赵明波,姜勇,&屠鹏飞.(2015).塔中栽培荒漠肉苁蓉中的木脂素类成分.中国中药杂志,40(3),463-468.
MLA	南泽东,et al."塔中栽培荒漠肉苁蓉中的木脂素类成分".中国中药杂志 40.3(2015):463-468.