干旱区生态环境知识资源中心(Arid): 超高效液相色谱-三重四极杆质谱联用同时检测环境水体中22种典型药品及个人护理用品

Arid

	超高效液相色谱-三重四极杆质谱联用同时检测环境水体中22种典型药品及个人护理用品
其他题名	Simultaneous determination of 22 typical pharmaceuticals and personal care products in environmental water using ultra performance liquid chromatography-triple quadrupole mass spectrometry
	吴春英 1; 谷风 2; 白鹭 2; 陆文龙 2
来源期刊	色谱
ISSN	1000-8713
出版年	2015
卷号	33 期号:8 页码:845-848
中文摘要	应用超高效液相色谱-三重四极杆质谱联用仪(UPLC-MS/MS)建立了环境水体中22种典型药品及个人护理用品(pharmaceuticals and personal care products, PPCPs)的分析方法。通过对固相萃取柱、淋洗液、色谱流动相等的优化,确定以Oasis HLB小柱为固相萃取柱、甲醇为淋洗液、水(0.1%甲酸)-甲醇(7∶3, v/v)为流动相进行水样预处理和色谱分离。在最优条件下,目标物在水中的回收率为73%~125%,相对标准偏差(RSDs)为8.8%~17.5%。各目标物的线性范围均为2~2000 mug/L,线性相关系数(R~2)不小于0.997。该方法具有检出限低、回收率高等优点,经实际样品测试,适用于环境水体中22种典型PPCPs的同时检测,可为微量有机物引起的水环境风险评价和控制的相关研究提供支持。
英文摘要	An analytical method for simultaneous determination of 22 typical pharmaceuticals and personal care products (PPCPs) in environmental water samples was developed by ultra performance liquid chromatography-triple quadrupole mass spectrometry (UPLC-MS/MS). An Oasis HLB solid phase extraction cartridge, methanol as washing solution, water containing 0.1% formic acid-methanol (7∶3, v/v) as the mobile phases were selected for sample pretreatment and chromatographic separation. Based on the optimized sample pretreatment procedures and separation condition, the target recoveries ranged from 73% to 125% in water with the relative standard deviations (RSDs) from 8.8% to 17.5%, and the linear ranges were from 2 to 2000 mug/L with correlation coefficients (R~2) not less than 0.997. The method can be applied to simultaneous determination of the 22 typical PPCPs in environmental water samples because of its low detection limits and high recoveries. It can provide support and help for the related research on water environmental risk assessment and control of the micro-organic pollutants.
中文关键词	固相萃取 ; 超高效液相色谱-串联质谱 ; 药品 ; 个人护理用品 ; 环境水
英文关键词	solid phase extraction (SPE) ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) pharmaceuticals personal care products (PPCPs) environmental water
语种	中文
国家	中国
收录类别	CSCD
WOS类目	CHEMISTRY ANALYTICAL
WOS研究方向	Chemistry
CSCD记录号	CSCD:5498193
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/233090
作者单位	1.吉林化工学院资源与环境工程学院, 环境模拟与污染控制国家重点联合实验室, 吉林 132022, 中国; 2.吉林化工学院资源与环境工程学院, 吉林 132022, 中国
推荐引用方式 GB/T 7714	吴春英,谷风,白鹭,等. 超高效液相色谱-三重四极杆质谱联用同时检测环境水体中22种典型药品及个人护理用品[J],2015,33(8):845-848.
APA	吴春英,谷风,白鹭,&陆文龙.(2015).超高效液相色谱-三重四极杆质谱联用同时检测环境水体中22种典型药品及个人护理用品.色谱,33(8),845-848.
MLA	吴春英,et al."超高效液相色谱-三重四极杆质谱联用同时检测环境水体中22种典型药品及个人护理用品".色谱 33.8(2015):845-848.