干旱区生态环境知识资源中心(Arid): 沈阳室内空气污染对儿童哮喘及相关症状的影响

Arid

	沈阳室内空气污染对儿童哮喘及相关症状的影响
其他题名	Effects of indoor air pollution on asthma and asthma - related symptoms among children in Shenyang city
	马亚楠 1; 赵洋 1; 刘玉芹 1; 刘苗苗 1; 王达 1; 任万辉 2; 高峰 2; 董光辉 1; 何钦成 1
来源期刊	中华预防医学杂志
ISSN	0253-9624
出版年	2013
卷号	47 期号:1 页码:49-54
中文摘要	目的探讨沈阳市室内空气污染及个体易感性对儿童哮喘及相关症状发生率的影响。方法于2007年4月采用整群随机抽样方法选取沈阳市内5个行政区,在每个行政区采用整群随机抽样法选取1所小学和2所幼儿园,对小于12周岁,在沈阳居住时间大于2年的汉族儿童进行调查,共调查了8733名儿童。采用美国胸科学会的调查表,对儿童的一般情况、哮喘和相关症状(包括喘鸣、喘鸣样症状、持续咳嗽、持续咯痰)、室内空气污染状况、儿童易感史等方面进行调查。应用_X2检验分析室内空气污染状况对哮喘及相关症状的影响,并使用logistic回归探讨各危险因素对易感、非易感儿童哮喘及相关症状发生率的影响。结果在调查的8733名儿童中,男性4420名(50.6%),女性4313名(49.4%),年龄为(8.082.88)岁。儿童哮喘、哮喘现患、咳嗽、持续咯痰、喘鸣及喘鸣样症状的发生率分别为6.4%(559例)、2.5%(215例)、9.6%(836例)、4.4%(386例)、17.5%(524例)、2.6%(229例)。其中哮喘、喘鸣样症状的发生率性别间的差异有统计学意义,男、女儿童哮喘的发生率分别为7.1%(313例)、5.7%(246例)(X~2 =6.916, P<0.05);喘鸣的发生率分别为19.2%(850例)、15.6%(674例)(X~2=19.678, P<0.05)。不同环境因素影响儿童哮喘发生率,其中2岁前被动吸烟、暴露于室内装修环境、家养皮毛宠物的儿童哮喘发生率分别为9.5%(159/1669)、8.0%(270/3367)、9.0%(114/1269),非暴露组发生率分别为5.7%(400/7064)、5.4%(289/5366)、6.0%(445/7464),差异有统计学意义(X~2值分别为33. 646、23. 944、16. 527, P值均< 0. 05) 。家族易感史及易感体质对儿童哮喘具有影响,其中具有家庭哮喘史、家庭过敏史和过敏体质史的儿童哮喘发生率分别为17.3%(106/613)、13.1%(85/647)、22.0%(147/668), 非暴露组发生率为5.5%(453/8120)、5.9%(474/8086)、5.1% (412/8065),差异有统计学意义(X~2值分别为130.522、59.929、293.997, P值均<0. 05)。采用logistic回归分析,在非易感儿童中2岁前被动吸烟(OR=1.7, 95% CI: 1.2~2.4)、室内装修(OR=1.5, 95% CI:1.1~1.9)和家养皮毛动物(OR= 1.6, 95% CI:1~2.3)可增加哮喘的患病风险。在易感儿童中仅有室内装修(OR=l.4, 95% CI:1.1~ 1. 7)和2岁前被动吸烟(OR=1.3, 95% CI:1.0-1.7)两个因素可增加哮喘患病风险。结论室内空气污染是儿童哮喘的危险因素;具有家族哮喘史和体质易感的儿童发生哮喘的危险性更高,并且易感儿童易受其他因素的影响。
英文摘要	Objective To study the effects of indoor air pollution and individual susceptible factors on prevalence of children’s asthma and asthma - related symptoms in Shenyang city. Methods On April, 2007, 8733 Han children who were under age of 12 and lived for more than 2 years in Shenyang city, were selected from five administrative areas (one primary school arid two kindergartens for each area) through cluster random sampling method. Information on children’s general condition, asthma and related symptoms(including stridor, stridor symptoms, persistent cough, persistent phlegm), indoor air pollution, and susceptibility history were obtained by a standard questionnaire from the American Thoracic Society. The effects of indoor air pollution on asthma and asthma-related symptoms was analyzed through X~2 test. Logistic regression was used to research the effects of risk factors on the prevalence of asthma and asthma-related symptoms of both susceptible and non-susceptible children. Results Among the 8733 subjects,4420 (50. 6%) were boy and 4313 (49.4%) were girl, with the age of (8.082.88) years old. The prevalence of asthma, current asthma, cough, persistent phlegm, stridor and stridor symptom were 6.4%(559 cases), 2.5% (215 cases), 9.6% (836 cases), 4.4% (386 cases), 17.5% (1524 cases) and 2. 6%(229 cases)respectively. The prevalence of asthma the boys and girls were among 7. 1% (313 cases) and5.7% (246 cases) (X2 =6. 916, P<0.05); and stridor symptom for them were 19.2% (850 cases), 15.6%(674 cases)(X~2 = 19. 678, P <0. 05), respectively. Passive smoking before two years old, house decoration and pet were related to asthma of children, and there was significant difference between the two groups. The prevalence of asthma of exposed children were 7.7% (312 cases), 9.5% (159 cases), 8.0% (270 cases), 9.0% (114 cases), respectively. Compared with the non-exposed children who had asthma, the prevalence of asthma were 5.7% (400 cases), 5.4% (289 cases), 6.0% (445 cases), the value of X~2 were 33. 646, 23. 944 and 16.527 respectively (all P values<0.05). Children who had family history of asthma, family history of allergy and allergy history were also related with asthma, the prevalence of asthma were 17.3% (106 cases), 13. 1% (85 cases), 22.0% (147 cases), compared with the non-exposed children who had asthma, the prevalence of asthma were 5.5% (453), 5.9% (474), 5.1% (412), and there was significant difference between the two groups, the value of X~2 were 130. 522, 59. 929 and 293. 997, respectively (all P values <0. 05). Logistic regression analysis showed that passive smoking(OR = 1.7, 95% CI:1.2-2. 4), house decoration(OR = 1.5, 95% CI:1.1 - 1.9) and pet(OR=1.6, 95% CI:1.1-2.3) were statistically significant to asthma in non-susceptible children. While passive smoking(OR = 1.3, 95% CI: 1.0 - 1.7) and house decoration(OR = 1.4, 95% CI: 1.1-1.7) were increased the risk of asthma. Conclusion Indoor air pollution is a risk factor of children’s asthma. Family history of asthma and physical susceptible children are high risk to asthma, and susceptible children are easily influenced by other risk factors.
中文关键词	空气污染 ; 室内 ; 儿童 ; 哮喘 ; 易感因素
英文关键词	Air pollution Indoor Child Asthma Susceptible factors
语种	中文
国家	中国
收录类别	CSCD
WOS类目	PUBLIC ENVIRONMENTAL OCCUPATIONAL HEALTH
WOS研究方向	Public, Environmental & Occupational Health
CSCD记录号	CSCD:4732130
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/230732
作者单位	1.中国医科大学公共卫生学院卫生统计教研室, 沈阳, 辽宁 110001, 中国; 2.沈阳市环境监测中心站
推荐引用方式 GB/T 7714	马亚楠,赵洋,刘玉芹,等. 沈阳室内空气污染对儿童哮喘及相关症状的影响[J],2013,47(1):49-54.
APA	马亚楠.,赵洋.,刘玉芹.,刘苗苗.,王达.,...&何钦成.(2013).沈阳室内空气污染对儿童哮喘及相关症状的影响.中华预防医学杂志,47(1),49-54.
MLA	马亚楠,et al."沈阳室内空气污染对儿童哮喘及相关症状的影响".中华预防医学杂志 47.1(2013):49-54.