干旱区生态环境知识资源中心(Arid): 塔中栽培荒漠肉苁蓉化学成分研究

Arid

	塔中栽培荒漠肉苁蓉化学成分研究
其他题名	Chemical constituents from stems of Cistanche deserticola cultured in Tarim desert
	南泽东; 赵明波; 姜勇; 屠鹏飞
来源期刊	中国中药杂志
ISSN	1001-5302
出版年	2013
卷号	38 期号:16 页码:2665-2670
中文摘要	对新疆塔中栽培荒漠肉苁蓉Cistanche deserticola Y.C.Ma干燥肉质茎的化学成分进行研究。采用正相硅胶、凝胶Sephadex LH-20,MCI,ODS以及半制备高效液相色谱等方法进行分离纯化,运用NMR,MS等波谱方法以及理化性质结合文献数据对分离得到的化合物进行结构鉴定。结果从塔中栽培荒漠肉苁蓉干燥肉质茎85%乙醇提取物中分离得到17个化合物,其结构鉴定为salsaside B(1)、紫丁香苷(2)、去甲基紫丁香苷(3)、松柏苷(4)、(2E,6E)-3,7-dimethyl-8-hydroxyoctadien-1-O-beta-D-glucoside(5)、(+)-丁香脂素(6)、2S,3S,4S-trihydroxy-pentanoic acid(7)、panaxytriol(8)、beta-谷甾醇-3-O-beta-D-吡喃木糖苷(9)、草夹竹桃苷(10)、3-methyl-but-2-en-1-yl-beta-D-glucopyranoside(11)、苄基葡萄糖苷(12)、4-羟基苄基-beta-D-葡萄糖苷(13)、烟酰胺(14)、对羟基苯甲酸(15)、对羟基苯乙醇(16)、半乳糖醇(17)。化合物3,6~13为首次从该属植物中分离得到,化合物1,4,5为首次从该种植物中分离得到。
英文摘要	In order to clarify the chemical constituents of Cistanche deserticola cultured in Tarim desert,a systematically phytochemical investigation was carried out. The chemical constituents were isolated by column chromatography,over silica gel,Sephadex LH-20,MCI gel,ODS and semi-preparative HPLC,and their structures were determined on the basis of MS,NMR spectroscopic data analysis,physicochemical properties and /or comparison with literature data. Seventeen compounds were isolated from the 85% ethanol extract of the stems of C. deserticola cultured in Tarim desert. Their structures were identified as salsaside B(1),syringin(2),demethyl syrinyin(3),coniferin(4),(2E,6E) -3,7-dimethyl-8-hydroxyoctadien-1-O-beta-D-glucoside(5),(+) -syringaresinol(6),2S,3S, 4S-trihydroxypentanoic acid(7),panaxytriol(8),beta-sitosterol-3-O-beta-D-xylopyranoside(9),androsin(10),3-methyl-but-2-en-1-yl-beta- D-glucopyranoside(11),benzyl-glucopyranoside (12),4-hydroxybenzyl-beta-D-glucoside (13),nicotinamide (14),p-hydroxybenzoic acid(15),4-hydroxy-benzeneethanol(16),and galactitol(17). Compounds 3,6-13 were isolated from this genus for the first time, and compounds 1,4 and 5 were obtained from this species for the first time.
中文关键词	荒漠肉苁蓉 ; 肉苁蓉属 ; 化学成分 ; 结构鉴定
英文关键词	Cistanche deserticola Cistanche chemical constituents structure elucidation
语种	中文
国家	中国
收录类别	CSCD
WOS类目	MEDICINE GENERAL INTERNAL
WOS研究方向	General & Internal Medicine
CSCD记录号	CSCD:4937142
来源机构	北京大学
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/230727
作者单位	北京大学, 天然药物及仿生药物国家重点实验室, 北京 100191, 中国
推荐引用方式 GB/T 7714	南泽东,赵明波,姜勇,等. 塔中栽培荒漠肉苁蓉化学成分研究[J]. 北京大学,2013,38(16):2665-2670.
APA	南泽东,赵明波,姜勇,&屠鹏飞.(2013).塔中栽培荒漠肉苁蓉化学成分研究.中国中药杂志,38(16),2665-2670.
MLA	南泽东,et al."塔中栽培荒漠肉苁蓉化学成分研究".中国中药杂志 38.16(2013):2665-2670.