干旱区生态环境知识资源中心(Arid): 气相色谱-串联质谱法测定木制儿童用品中的10种木材防腐剂

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	气相色谱-串联质谱法测定木制儿童用品中的10种木材防腐剂
其他题名	Determination of 10 Preservatives in Wooden Children’s Products by Gas Chromatography-Tandem Mass Spectrometry
	吕庆 1; 李海玉 1; 李丕 1; 李文涛 1; 郭项羽 1; 王烨 1; 白桦 1; 齐美玲 2; 张庆 1
来源期刊	质谱学报
ISSN	1004-2997
出版年	2013
卷号	34 期号:6 页码:321-329
中文摘要	建立了固相萃取-气相色谱-串联质谱法(SPE-GC-MS/MS)同时测定木制儿童用品中氯酚类化合物和菊酯类化合物等10种木材防腐剂。采用甲醇溶剂提取,乙酸酐试剂衍生、固相萃取净化后,经HP-5MS色谱柱(30 m0.25 mm0.25 mum)分离,串联质谱在多反应离子监测模式(MRM)下进行检测,内标法定量。同时,考察了多种实验参数对检测结果的影响,并进行方法验证。结果表明,该方法对于复杂基质的木材样品中目标物的检测具有良好的选择性与灵敏度。对于不同物质的定量限(LOQ)在0.002 5~0.2 mg/kg之间,线性范围为0.002 5~25 mg/kg,低、中、高3个添加水平的平均回收率在85.2%~100.1%之间,日内精密度(RSD,n=6)在0.6%~9.1%之间,日间精密度(RSD,n=6)在2.3%~7.2%之间。将该方法应用于实际样品抽查中,发现了多种木材防腐剂的残留。
英文摘要	Ten kinds of wood preservatives of chlorophenols and pyrethroids in wooden children’s products were determined simultaneously using solid phase extraction coupled with gas chromatography-tandem mass spectrometry (SPE-GC-MS/MS). The sample was ultrasonically extracted with methanol. The extract was evaporated and then derivatised with acetic anhydride. Finally the solution was purified using Oasis HLB SPE column. The separations were performed on an Agilent HP-5MS column (30 m0.25 mm0.25 mum), then were determined by MS/MS and quantified by internal standard method. Procedures for extraction and purification were carefully optimized. The method was proved to be linear over a wide range of concentrations for all analytes with the correlation coefficients greater than 0.999 3. Limits of detection (LODs) and limits of quantification (LOQs) are in the range of 0.0010.05 mg/kg and 0.002 50.2 mg/kg, respectively. Average recoveries of target compounds (spiked at three concentration levels) are in the range of 85.2%100.1%. Intraday and interday repeatability (RSD, n=6) of the proposed method are vary of 0.6%9.1% and 2.3%7.2%, respectively. The proposed method was used to monitor preservatives in commercial wooden toys, and some preservatives were found.
中文关键词	气相色谱-串联质谱法 ; 木材防腐剂 ; 固相萃取 ; 木制儿童用品
英文关键词	gas chromatography-tandem mass spectrometry wood preservatives solid phase extraction wooden children’s products
语种	中文
国家	中国
收录类别	CSCD
WOS类目	CHEMISTRY ANALYTICAL
WOS研究方向	Chemistry
CSCD记录号	CSCD:4993052
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/230466
作者单位	1.中国检验检疫科学研究院,工业与消费品安全研究所, 北京 100123, 中国; 2.北京理工大学化学学院, 北京 100081, 中国
推荐引用方式 GB/T 7714	吕庆,李海玉,李丕,等. 气相色谱-串联质谱法测定木制儿童用品中的10种木材防腐剂[J],2013,34(6):321-329.
APA	吕庆.,李海玉.,李丕.,李文涛.,郭项羽.,...&张庆.(2013).气相色谱-串联质谱法测定木制儿童用品中的10种木材防腐剂.质谱学报,34(6),321-329.
MLA	吕庆,et al."气相色谱-串联质谱法测定木制儿童用品中的10种木材防腐剂".质谱学报 34.6(2013):321-329.