干旱区生态环境知识资源中心(Arid): 液相色谱-串联质谱法快速测定饮用水中6种雌激素

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	液相色谱-串联质谱法快速测定饮用水中6种雌激素
其他题名	Determination of Six Estrogens in Drinking Water by Liquid Chromatography-Mass Spectrometry
	贾彦博; 王红青; 韩里明
来源期刊	分析测试学报
ISSN	1004-4957
出版年	2011
卷号	30 期号:7 页码:808-812
中文摘要	建立了液相色谱-质谱法测定饮用水中17-beta-雌二醇、17-alpha-雌二醇、17-alpha-乙炔雌二醇、己烷雌酚（HEX）、己烯雌酚（DES）和双烯雌酚（DE）6种雌激素的分析方法。样品经乙腈萃取,Oasis HLB柱富集净化后,采用液相色谱-质谱法测定。方法在5100mug/L范围内呈良好线性,相关系数为0.9941.000,6种激素的检出限均为0.1mug/L。在0.10、25、50mug/L 3个加标水平下,6种雌激素的加标回收率为85%95%,相对标准偏差（RSD）均小于10%。该方法有效地消除了基质干扰,样品处理快、灵敏度高,适用于饮用水中雌激素的日常批量检测和确证。
英文摘要	A liquid chromatography-mass spectrometric(LC-MS)method was established for the determination of six estrogens in drinking water.The sample was extracted with acetonitrile,enriched by Oasis HLB solid-phase extraction column,and then analyzed by LC-MS.Under the optimal conditions,good linearities were obtained in the range of 5-100 mug/L for six estrogens with correlation coefficients of 0.994-1.000.The detection limits for 6 estrogens were all 0.1 mug/L.The recoveries at three spiked levels of 0.10,25,50 mug/L were between 85% and 95% with relative standard deviations less than 10%.With the advantages of high sensitivity and simple sample preparation without matrix interference,the method was suitable for the analysis of the estrogens in drink water.
中文关键词	饮用水 ; 雌激素 ; 液相色谱-串联质谱
英文关键词	drinking water estrogen liquid chromatography-mass spectrometry(LC-MS)
语种	中文
国家	中国
收录类别	CSCD
WOS类目	CHEMISTRY ANALYTICAL
WOS研究方向	Chemistry
CSCD记录号	CSCD:4267190
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/226368
作者单位	杭州市质量技术监督检测院, 国家水产品及加工食品质量监督检验中心, 杭州, 浙江 310019, 中国
推荐引用方式 GB/T 7714	贾彦博,王红青,韩里明. 液相色谱-串联质谱法快速测定饮用水中6种雌激素[J],2011,30(7):808-812.
APA	贾彦博,王红青,&韩里明.(2011).液相色谱-串联质谱法快速测定饮用水中6种雌激素.分析测试学报,30(7),808-812.
MLA	贾彦博,et al."液相色谱-串联质谱法快速测定饮用水中6种雌激素".分析测试学报 30.7(2011):808-812.