干旱区生态环境知识资源中心(Arid): 头颈部Kimura 病的临床病理特点与诊断

Arid

	头颈部Kimura 病的临床病理特点与诊断
其他题名	Clinicopathologic features and diagnosis of Kimura diseases in head and neck region
	姜蕾 1; 姜晓钟 1; 赵云富 1; 何金 2; 刘渊 1; 吴洋 1; 周洁 1; 黄建涛 1; 王国栋 1
ISSN	1001-7399
出版年	2007
卷号	23 期号:3 页码:321-323
中文摘要	目的探讨头颈部Kimura病(Kimura′s disease,KD)的临床病理特点.方法对10例发生在头颈部的KD病临床资料、发病年龄、病理表现、实验室检查等进行回顾性分析.结果10例KD者临床上主要表现为头颈部无明显压痛的软组织包块.组织学上以小血管增生、大量嗜酸性粒细胞浸润、淋巴细胞增生及滤泡形成、生发中心扩大、纤维组织增生为基本病变.结论KD是一种具有特殊临床病理表现的炎性增生性病变,应与部分富含淋巴组织的肿瘤相鉴别,组织病理学对于诊断有着十分重要的意义.免疫组化结果显示KD是一种多克隆淋巴结炎性病变,提示细胞异常增殖与凋亡的抑制共同发挥作用.
英文摘要	Purpose To study the clinicopathologic features of Kimura’s disease (KD) . Methods A retrospective study was conducted in 10 cases of KD in their clinical data, ages, histopathologic features, and laboratory findings. Results Among the 10 oases, the typical clinical presentation was characterized by painless soft tissue masses predominantly in the head or neck region. Histologically, basic pathologic changes were characterized by vascular proliferation, marked eosinophilic infiltration, lymphocytic proliferation, lymphatic follicles, fibroplasias and enlargement of germinal center. Conclusions KD is a benign disease with characteristic inflammatory proliferation in histopathology. It should be differentiated from tumor abundant with fat tissue. The histopathologic diagnosis of KD is important. Immunohistochemistry shows a multi colonal inflammatory disease of the lymph node, indicating a coordination of abnormal proliferation of cells and inhibition of apoptosis.
中文关键词	Kimura病 ; 嗜酸细胞肉芽肿 ; 病理学
英文关键词	Kimura’s disease eosinophilic granuloma pathology
语种	中文
国家	中国
收录类别	CSCD
WOS类目	ONCOLOGY
WOS研究方向	Oncology
CSCD记录号	CSCD:2817620
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/221206
作者单位	1.第二军医大学附属长征医院口腔科, 上海 200003, 中国; 2.第二军医大学附属长征医院病理科, 上海 200003, 中国
推荐引用方式 GB/T 7714	姜蕾,姜晓钟,赵云富,等. 头颈部Kimura 病的临床病理特点与诊断[J],2007,23(3):321-323.
APA	姜蕾.,姜晓钟.,赵云富.,何金.,刘渊.,...&王国栋.(2007).头颈部Kimura 病的临床病理特点与诊断.,23(3),321-323.
MLA	姜蕾,et al."头颈部Kimura 病的临床病理特点与诊断".23.3(2007):321-323.