干旱区生态环境知识资源中心(Arid): The sero-epidemiology of Coxiella burnetii (Q fever) across livestock species and herding contexts in Laikipia County, Kenya

Arid

DOI	10.1111/zph.12567
	The sero-epidemiology of Coxiella burnetii (Q fever) across livestock species and herding contexts in Laikipia County, Kenya
	Larson, Peter S.1,2; Espira, Leon 2; Grabow, Cole 2; Wang, Christine A.3; Muloi, Dishon 4,5,6; Browne, A. Springer 7; Deem, Sharon L.7; Fevre, Eric M.5,8; Foufopoulos, Johannes 1; Hardin, Rebecca 1; Eisenberg, Joseph N. S.2
通讯作者	Eisenberg, Joseph N. S.
来源期刊	ZOONOSES AND PUBLIC HEALTH
ISSN	1863-1959
EISSN	1863-2378
出版年	2019
卷号	66 期号:3 页码:316-324
英文摘要	Coxiella burnetii, the causative agent of Query fever (Q fever), is among the most highly infectious zoonotic pathogens transmitted among livestock, with chronic effects challenging to veterinary and medical detection and care systems. Transmission among domestic livestock species can vary regionally due to herd management practices that determine which livestock species are raised, whether or not livestock are in contact with wildlife, and the susceptibility of these livestock to infection. To explore how different livestock management practices are associated with the risk of infection in multispecies environments, we carried out a comparative study of three types of herd management systems in the central Kenyan county of Laikipia: agro-commercial, mixed conservancy/commercial, and smallholder ranches. We tested C. burnetii antibody seroprevalence in four common livestock species. Across all management types, the highest seroprevalence was in camels (20%), followed by goats (18%), sheep (13%), and cattle (6%). We observed a lower odds of testing seropositive for young compared to adult animals (adjusted OR = 0.44 [95% CI 0.24, 0.76]), and for males compared to females (adjusted OR = 0.52 [95% CI 0.33, 0.80]). Animals from mixed conservancy/commercial and smallholder operations had a higher odds of testing seropositive compared to animals from agro-commercial ranches (adjusted OR = 5.17 [95% CI 2.71, 10.44] and adjusted OR = 2.21 [95% CI 1.17, 4.43] respectively). These data suggest that herd management practices might affect the transmission dynamics of C. burnetiiin arid African ecosystems like those seen in Kenya where several transmission modes are possible, risk of drought has promoted new livestock species such as camels, and multiple wildlife species may co-occur with livestock on the landscape. Further longitudinal studies are needed to disentangle the mechanisms underlying these patterns, and further explore transmission patterns between wildlife, domestic animal, and human populations.
英文关键词	Kenya land management livestock economy Q fever seroepidemiology zoonosis
类型	Article
语种	英语
国家	USA ; Scotland ; Kenya ; England
开放获取类型	Green Published, hybrid
收录类别	SCI-E
WOS记录号	WOS:000464342300007
WOS关键词	BULK TANK MILK ; ANTIBODIES ; CATTLE ; TICKS ; RISK ; BRUCELLOSIS ; PREVALENCE ; HUMANS
WOS类目	Public, Environmental & Occupational Health ; Infectious Diseases ; Veterinary Sciences
WOS研究方向	Public, Environmental & Occupational Health ; Infectious Diseases ; Veterinary Sciences
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/219368
作者单位	1.Univ Michigan, Sch Environm & Sustainabil, Ann Arbor, MI 48109 USA; 2.Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA; 3.North Carolina State Univ, Coll Vet Med, Dept Populat Hlth & Pathobiol, Raleigh, NC USA; 4.Univ Edinburgh, Ctr Immun Infect & Evolut, Edinburgh, Midlothian, Scotland; 5.Int Livestock Res Inst, Nairobi, Kenya; 6.Univ Edinburgh, Usher Inst Populat Hlth Sci & Informat, Edinburgh, Midlothian, Scotland; 7.St Louis Zoo Inst Conservat Med, St Louis, MO USA; 8.Univ Liverpool, Inst Infect & Global Hlth, Liverpool, Merseyside, England
推荐引用方式 GB/T 7714	Larson, Peter S.,Espira, Leon,Grabow, Cole,et al. The sero-epidemiology of Coxiella burnetii (Q fever) across livestock species and herding contexts in Laikipia County, Kenya[J],2019,66(3):316-324.
APA	Larson, Peter S..,Espira, Leon.,Grabow, Cole.,Wang, Christine A..,Muloi, Dishon.,...&Eisenberg, Joseph N. S..(2019).The sero-epidemiology of Coxiella burnetii (Q fever) across livestock species and herding contexts in Laikipia County, Kenya.ZOONOSES AND PUBLIC HEALTH,66(3),316-324.
MLA	Larson, Peter S.,et al."The sero-epidemiology of Coxiella burnetii (Q fever) across livestock species and herding contexts in Laikipia County, Kenya".ZOONOSES AND PUBLIC HEALTH 66.3(2019):316-324.