干旱区生态环境知识资源中心(Arid): An autochthonous case of paracoccidioidomycosis in a new area of Ceara State, Northeastern Brazil

Arid

DOI	10.1590/S1678-9946201961058
	An autochthonous case of paracoccidioidomycosis in a new area of Ceara State, Northeastern Brazil
	de Lima Mota, Matheus Alves 1,2; Damasceno, Lisandra Serra 1,3; Bandeira, Silviane Praciano 4; Jesus Silva Leitao, Terezinha do Menino 1,3
通讯作者	de Lima Mota, Matheus Alves
来源期刊	REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO
ISSN	0036-4665
EISSN	1678-9946
出版年	2019
卷号	61
英文摘要	The largest endemic areas of paracoccidioidomycosis (PCM) in Brazil comprise the humid agricultural regions of the Southeast, South. and, recently, the Midwest and North regions. The Ceara State, located in the Brazilian Northeast region, presents semi-arid climate in most of its territory, characterized by high temperatures, scarce vegetation and low humidity. The objective of the present study was to describe a new autochthonous case of paracoccidioidomycosis from a distinct area of Ceara and review the characteristics of PCM occurrence in Northeastern Brazil. The patient was a 65-year-old male farmer who denied traveling outside the Ceara State or living in other locations. He was born and lived in the rural area known as Camara, bordering the municipalities of Itapaje and Itapipoca. Camara is one of the highest areas (around 720 m of altitude) of the Uruburetama mountains that exhibits tropical forests and is located in Northern Ceara, distant 139 km from the capital, Fortaleza. The patient sought for care, complaining of an oral lesion that appeared over the past three years. The hard palate lesion biopsy revealed multinucleated cells with cytoplasmic inclusions, compatible with PCM. After culture. P brasiliensis was identified by polymerase chain reaction. Serological testing for PCM was reagent. The patient was treated with itraconazole for approximately 17 months, persisting free of symptoms after 15 months of follow-up. Regarding this new autochthonous case in the Ceara State. PCM should be considered in the differential diagnosis of patients with suggestive clinical manifestations. proceeding from the mountainous areas of Ceara.
英文关键词	Fungal diseases Paracoccidioidomycosis Ceara Northeastern Brazil P. brasiliensis
类型	Article
语种	英语
国家	Brazil
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000489611000006
WOS类目	Infectious Diseases ; Parasitology ; Tropical Medicine
WOS研究方向	Infectious Diseases ; Parasitology ; Tropical Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/218507
作者单位	1.Hosp Sao Jose Doencas Infecciosas, Fortaleza, Ceara, Brazil; 2.Univ Fortaleza, Fac Med, Av Washington Soares 1321, BR-60811905 Fortaleza, Ceara, Brazil; 3.Univ Fed Ceara, Fac Med, Dept Saude Comunitaria, Fortaleza, Ceara, Brazil; 4.Univ Fed Ceara, Fac Med, Dept Patol & Med Legal, Fortaleza, Ceara, Brazil
推荐引用方式 GB/T 7714	de Lima Mota, Matheus Alves,Damasceno, Lisandra Serra,Bandeira, Silviane Praciano,et al. An autochthonous case of paracoccidioidomycosis in a new area of Ceara State, Northeastern Brazil[J],2019,61.
APA	de Lima Mota, Matheus Alves,Damasceno, Lisandra Serra,Bandeira, Silviane Praciano,&Jesus Silva Leitao, Terezinha do Menino.(2019).An autochthonous case of paracoccidioidomycosis in a new area of Ceara State, Northeastern Brazil.REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO,61.
MLA	de Lima Mota, Matheus Alves,et al."An autochthonous case of paracoccidioidomycosis in a new area of Ceara State, Northeastern Brazil".REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO 61(2019).