Knowledge Resource Center for Ecological Environment in Arid Area
| DOI | 10.1073/pnas.1720938116 |
| Genomic divergence and adaptive convergence in Drosophila simulans from Evolution Canyon, Israel | |
| Kang, Lin1; Rashkovetsky, Eugenia2; Michalak, Katarzyna3; Garner, Harold R.1,4; Mahaney, James E.1; Rzigalinski, Beverly A.1; Korol, Abraham2; Nevo, Eviatar2; Michalak, Pawel1,2,3,5 | |
| 通讯作者 | Nevo, Eviatar ; Michalak, Pawel |
| 来源期刊 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
 |
| ISSN | 0027-8424 |
| 出版年 | 2019 |
| 卷号 | 116期号:24页码:11839-11844 |
| 英文摘要 | Biodiversity refugia formed by unique features of the Mediterranean arid landscape, such as the dramatic ecological contrast of Evolution Canyon, provide a natural laboratory in which local adaptations to divergent microclimate conditions can be investigated. Significant insights have been provided by studies of Drosophila melanogaster diversifying along the thermal gradient in Evolution Canyon, but a comparative framework to survey adaptive convergence across sister species at the site has been lacking. To fill this void, we present an analysis of genomic polymorphism and evolutionary divergence of Drosophila simulans, a close relative of Drosophila melanogaster with which it co-occurs on both slopes of the canyon. Our results show even deeper interslope divergence in D. simulans than in D. melanogaster, with extensive signatures of selective sweeps present in flies from both slopes but enhanced in the population from the hotter and drier south-facing slope. Interslope divergence was enriched for genes related to electrochemical balance and transmembrane transport, likely in response to increased selection for dehydration resistance on the hotter slope. Both species shared genomic regions that underwent major selective sweeps, but the overall level of adaptive convergence was low, demonstrating no shortage of alternative genomic solutions to cope with the challenges of the microclimate contrast. Mobile elements were a major source of genetic polymorphism and divergence, affecting all parts of the genome, including coding sequences of mating behavior-related genes. |
| 英文关键词 | adaptive evolution selective sweeps evolutionary convergence local adaptations |
| 类型 | Article |
| 语种 | 英语 |
| 国家 | USA ; Israel |
| 开放获取类型 | Green Published, hybrid |
| 收录类别 | SCI-E |
| WOS记录号 | WOS:000471039700046 |
| WOS关键词 | DETECTING SELECTIVE SWEEPS ; MELANOGASTER POPULATIONS ; GENE-EXPRESSION ; STRESS ; DIFFERENTIATION ; ADAPTATION ; MICROSITE ; DIVERSITY ; RESPONSES ; CONTRAST |
| WOS类目 | Multidisciplinary Sciences |
| WOS研究方向 | Science & Technology - Other Topics |
| 资源类型 | 期刊论文 |
| 条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/218178 |
| 作者单位 | 1.Edward Via Coll Osteopath Med, Blacksburg, VA 24060 USA; 2.Univ Haifa, Inst Evolut, IL-3498838 Haifa, Israel; 3.Virginia Tech, Biocomplex Inst, Blacksburg, VA 24061 USA; 4.Gibbs Canc Ctr & Res Inst, Spartanburg, SC 29303 USA; 5.Virginia Maryland Coll Vet Med, Ctr One Hlth Res, Blacksburg, VA 24060 USA |
| 推荐引用方式 GB/T 7714 | Kang, Lin,Rashkovetsky, Eugenia,Michalak, Katarzyna,et al. Genomic divergence and adaptive convergence in Drosophila simulans from Evolution Canyon, Israel[J],2019,116(24):11839-11844. |
| APA | Kang, Lin.,Rashkovetsky, Eugenia.,Michalak, Katarzyna.,Garner, Harold R..,Mahaney, James E..,...&Michalak, Pawel.(2019).Genomic divergence and adaptive convergence in Drosophila simulans from Evolution Canyon, Israel.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,116(24),11839-11844. |
| MLA | Kang, Lin,et al."Genomic divergence and adaptive convergence in Drosophila simulans from Evolution Canyon, Israel".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116.24(2019):11839-11844. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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