干旱区生态环境知识资源中心(Arid): Evaluation of the intra- and inter-method agreement of brain MRI segmentation software packages: A comparison between SPM12 and FreeSurfer v6.0

Arid

DOI	10.1016/j.ejmp.2019.07.016
	Evaluation of the intra- and inter-method agreement of brain MRI segmentation software packages: A comparison between SPM12 and FreeSurfer v6.0
	Palumbo, L.1; Bosco, P.1; Fantacci, M. E.2; Ferrari, E.1,3; Oliva, P.4,5; Spera, G.1; Retico, A.1
通讯作者	Palumbo, L.
来源期刊	PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
ISSN	1120-1797
EISSN	1724-191X
出版年	2019
卷号	64 页码:261-272
英文摘要	Purpose: The lack of inter-method agreement can produce inconsistent results in neuroimaging studies. We evaluated the intra-method repeatability and the inter-method reproducibility of two widely-used automatic segmentation methods for brain MRI: the FreeSurfer (FS) and the Statistical Parametric Mapping (SPM) software packages. Methods: We segmented the gray matter (GM), the white matter (WM) and subcortical structures in test-retest MRI data of healthy volunteers from Kirby-21 and OASIS datasets. We used Pearson's correlation (r), Bland-Altman plot and Dice index to study intra-method repeatability and inter-method reproducibility. In order to test whether different processing methods affect the results of a neuroimaging-based group study, we carried out a statistical comparison between male and female volume measures. Results: A high correlation was found between test-retest volume measures for both SPM (r in the 0.98-0.99 range) and FS (r in the 0.95-0.99 range). A non-null bias between test-retest FS volumes was detected for GM and WM in the OASIS dataset. The inter-method reproducibility analysis measured volume correlation values in the 0.72-0.98 range and the overlap between the segmented structures assessed by the Dice index was in the 0.76-0.83 range. SPM systematically provided significantly greater GM volumes and lower WM and subcortical volumes with respect to FS. In the male vs. female brain volume comparisons, inconsistencies arose for the OASIS dataset, where the gender-related differences appear subtler with respect to the Kirby dataset. Conclusions: The inter-method reproducibility should be evaluated before interpreting the results of neuroimaging studies.
英文关键词	Brain MRI Segmentation Repeatability Reproducibility
类型	Article
语种	英语
国家	Italy
收录类别	SCI-E
WOS记录号	WOS:000485006200033
WOS关键词	HEAD-SIZE ; VOLUME ; HIPPOCAMPAL ; GENDER ; AGE
WOS类目	Radiology, Nuclear Medicine & Medical Imaging
WOS研究方向	Radiology, Nuclear Medicine & Medical Imaging
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/217949
作者单位	1.Natl Inst Nucl Phys INFN, Pisa Div, Largo Bruno Pontecorvo 3, I-56127 Pisa, Italy; 2.Univ Pisa, Phys Dept, Pisa, Italy; 3.Scuola Normale Super Pisa, Pisa, Italy; 4.Univ Sassari, Sassari, Italy; 5.INFN, Cagliari Div, Cagliari, Italy
推荐引用方式 GB/T 7714	Palumbo, L.,Bosco, P.,Fantacci, M. E.,et al. Evaluation of the intra- and inter-method agreement of brain MRI segmentation software packages: A comparison between SPM12 and FreeSurfer v6.0[J],2019,64:261-272.
APA	Palumbo, L..,Bosco, P..,Fantacci, M. E..,Ferrari, E..,Oliva, P..,...&Retico, A..(2019).Evaluation of the intra- and inter-method agreement of brain MRI segmentation software packages: A comparison between SPM12 and FreeSurfer v6.0.PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS,64,261-272.
MLA	Palumbo, L.,et al."Evaluation of the intra- and inter-method agreement of brain MRI segmentation software packages: A comparison between SPM12 and FreeSurfer v6.0".PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS 64(2019):261-272.