干旱区生态环境知识资源中心(Arid): Neonatal mortality associated with sodium monofluoracetate in kids fed with colostrum from goats ingesting Amorimia septentrionalis

Arid

DOI	10.1590/1678-5150-PVB-5949
	Neonatal mortality associated with sodium monofluoracetate in kids fed with colostrum from goats ingesting Amorimia septentrionalis
	Lopes, Jose R. G.1; Araujo, Jose A. S.2; Pessoa, Danielle A. N.1; Lee, Stephen 3; Cook, Daniel 3; Riet-Correa, Franklin 1,4; Medeiros, Rosane M. T.1
通讯作者	Lopes, Jose R. G.
来源期刊	PESQUISA VETERINARIA BRASILEIRA
ISSN	0100-736X
EISSN	1678-5150
出版年	2019
卷号	39 期号:3 页码:163-167
英文摘要	Sudden deaths after colostrum ingestion in kids and lambs born to mothers grazing in areas with Amorimia septentrionalis have been reported in the Brazilian northeastern semi-arid region, in Paraiba state. This study aimed to determine whether the sodium monofluoracetate (MF) contained in A. septentrionalis is eliminated in milk, causing the death of kids. After confirming gestation on the 25th day after mating, 26 goats were randomly distributed into three groups. In Group 1, eight goats received fresh leaves of A. septentrionalis in daily doses of 1g/kg body weight, administered at three different periods during gestation: from days 91 to 100, 116 to 125, and from day 140 until delivery day. In Group 2, consisting of 10 females, eight goats received 1g/kg body weight of A. septentrionalis dried and milled leaves, fed daily from the 140th day of gestation until delivery. The other two goats of this group did not ingest the plant during gestation and after delivery the colostrum supplied to their kids was replaced by colostrum of goats from that same group that had ingested the plant. Eight goats from Group 3 (control) did not ingest A. septentrionalis. Seven goats from Group 1 showed signs of poisoning from 2nd to 8th days of plant administration, in all periods, and recovered within 7 to 12 days. Another goat presented severe clinical signs and was submitted to euthanasia in extremis. Two goats aborted. Four kids, from two goats, received colostrum and, after 15 minutes, presented depression, breathing wheezing, lateral recumbence, bleating, and death. Two goats gave birth at night; the two kids were found dead and, at necropsy, it was verified that they were born alive. The last goat in this group gave birth to two kids which showed no signs of poisoning after colostrum ingestion. In Group 2, the eight goats that ingested dry leaves of the plant presented tachycardia and engorgement of the jugular veins; six aborted, and the kids of the other two goats died immediately after delivery without ingesting colostrum. The three kids of the two goats that did not ingest the plant during gestation did not show signs of poisoning after ingesting colostrum from the goats that had ingested the plant. In Group 3, all females kidded normally and the kids showed no signs of poisoning. Ten leaf samples of A. septentrionalis contained 0.00074% +/- 0.00018 MF. These results demonstrate that the MF of A. septentrionalis is eliminated in colostrum and may cause the death of kids. As in previous reports, the plant also caused abortion.
英文关键词	Neonatal mortality sodium monofluoracetate colostrum goats kids Amorimia septentrionalis toxins in milk abortion plant poisoning toxicoses
类型	Article
语种	英语
国家	Brazil ; USA ; Uruguay
开放获取类型	gold, Green Submitted
收录类别	SCI-E
WOS记录号	WOS:000463334100001
WOS关键词	MONOFLUOROACETATE ; FIBROSIS
WOS类目	Veterinary Sciences
WOS研究方向	Veterinary Sciences
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/217930
作者单位	1.UFCG, Hosp Vet, CSTR, Ave Univ S-N, BR-58780110 Patos de Minas, PB, Brazil; 2.Escola Super Batista Amazonas ESBAM, Rua Leonor Teles 153, BR-69057510 Manaus, Amazonas, Brazil; 3.ARS, Poisonous Plant Res Lab, USDA, Univ Hill Way, Logan, UT 84322 USA; 4.INIA, Ruta 50 Km 11, La Estanzuela, Uruguay
推荐引用方式 GB/T 7714	Lopes, Jose R. G.,Araujo, Jose A. S.,Pessoa, Danielle A. N.,et al. Neonatal mortality associated with sodium monofluoracetate in kids fed with colostrum from goats ingesting Amorimia septentrionalis[J],2019,39(3):163-167.
APA	Lopes, Jose R. G..,Araujo, Jose A. S..,Pessoa, Danielle A. N..,Lee, Stephen.,Cook, Daniel.,...&Medeiros, Rosane M. T..(2019).Neonatal mortality associated with sodium monofluoracetate in kids fed with colostrum from goats ingesting Amorimia septentrionalis.PESQUISA VETERINARIA BRASILEIRA,39(3),163-167.
MLA	Lopes, Jose R. G.,et al."Neonatal mortality associated with sodium monofluoracetate in kids fed with colostrum from goats ingesting Amorimia septentrionalis".PESQUISA VETERINARIA BRASILEIRA 39.3(2019):163-167.