干旱区生态环境知识资源中心(Arid): Rhinoclactones A-E, Resorcylic Acid Analogs from Desert Plant Endophytic Fungus Rhinocladiella similis

Arid

DOI	10.3390/molecules24071405
	Rhinoclactones A-E, Resorcylic Acid Analogs from Desert Plant Endophytic Fungus Rhinocladiella similis
	Li, Luying 1,2; Zhang, Xiaoyan 1,2; Tan, Xiangmei 1,2; Sun, Bingda 3; Wu, Bin 1,2; Yu, Meng 1,2; Zhang, Tao 1,2; Zhang, Yonggang 4; Ding, Gang 1,2
通讯作者	Wu, Bin ; Zhang, Yonggang ; Ding, Gang
来源期刊	MOLECULES
ISSN	1420-3049
出版年	2019
卷号	24 期号:7
英文摘要	Seven resorcylic acid lactones (RALs) including five new analog rhinoclactones, A-E (1, 2, 4-6), were isolated from an endophytic fungus Rhinocladiella similis in the plant Agriophyllum squarrosum collected from the Tengger Desert of the Ningxia Province, China. The structures of these new compounds were determined by HR-ESI-MS (High Resolution Electrospray Ionization Mass Spectrometry), NMR data, modified Mosher's method, and X-ray diffraction experiments. All compounds isolated from this fungus possessed the 16-OMe/14-OH, not the common 16-OH/14-OH or 16-OH/14-OMe groups on the aromatic ring, which are rarely found in nature. Compound 7 displayed cytotoxic activities against HCT116 and HeLa cancer cell lines. The possible biosynthesis of 1-7 is suggested, and the potential ecological roles of these fungal secondary metabolites is discussed.
英文关键词	desert plant Agriophyllum squarrosum endophytic fungus Rhinocladiella similis rhinoclactones cytotoxic activities
类型	Article
语种	英语
国家	Peoples R China
开放获取类型	Green Submitted, Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000464944500007
WOS关键词	LACTONES
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/217681
作者单位	1.Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China; 2.Peking Union Med Coll, Beijing 100193, Peoples R China; 3.Chinese Acad Sci, Inst Microbiol, Beijing 100101, Peoples R China; 4.Qilu Univ Technol, Shandong Acad Sci, Biol Inst, Jinan 250353, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Li, Luying,Zhang, Xiaoyan,Tan, Xiangmei,et al. Rhinoclactones A-E, Resorcylic Acid Analogs from Desert Plant Endophytic Fungus Rhinocladiella similis[J],2019,24(7).
APA	Li, Luying.,Zhang, Xiaoyan.,Tan, Xiangmei.,Sun, Bingda.,Wu, Bin.,...&Ding, Gang.(2019).Rhinoclactones A-E, Resorcylic Acid Analogs from Desert Plant Endophytic Fungus Rhinocladiella similis.MOLECULES,24(7).
MLA	Li, Luying,et al."Rhinoclactones A-E, Resorcylic Acid Analogs from Desert Plant Endophytic Fungus Rhinocladiella similis".MOLECULES 24.7(2019).