干旱区生态环境知识资源中心(Arid): GC-MS Analysis, DPPH & Enzyme Inhibition Assays of Trianthema triquetra Rottl. and Willd. Growing in Pakistan

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	GC-MS Analysis, DPPH & Enzyme Inhibition Assays of Trianthema triquetra Rottl. and Willd. Growing in Pakistan
	Khurshid, Umair 1; Ahmad, Saeed 1; Rehman, Tayyeba 2; Arshad, Muhammad A.1; Pervaiz, Irfan 1; Saba, Sahar 1
通讯作者	Khurshid, Umair
来源期刊	LATIN AMERICAN JOURNAL OF PHARMACY
ISSN	0326-2383
出版年	2019
卷号	38 期号:6 页码:1181-1187
英文摘要	Trianthema triquetra Rottl. & Willd. (Aizoaceae) is a desert plant of Pakistan that has been traditionally used for various skin ailments, liver diseases, chronic fever, gout and amenorrhea. The plant has not been explored for phytochemicals or pharmacology yet. The aim of the study is to conduct gas chromatography-mass spectrometry (GC-MS) method and preliminary DPPH and enzyme inhibition assays for T. triquetra extract/fractions for identification of active principle and providing the basis of drug discovery. GC-MS analysis of T. triquetra led to the identification of seventeen compounds. These constituents include 9,12-octadecadienoic acid (Z,Z)-, methyl ester (20.324%), hexadecanoic acid, methyl ester (16.082%), 9-octadecenoic acid (Z)-, methyl ester (13.604%), 9,12-octadecadienoic acid, ethyl ester (10.134%), hexadecanoic acid, ethyl ester (9.102%), ethyl oleate (7.786%), 1,2-benzenedicarboxylic acid, mono (2-ethylhexyl) ester (7.732%), and vitamin E (3.590%). The n-hexane fraction showed the best activity against DPPH with 82.4%, while all the extract/fractions exhibited moderate tyrosinase, xanthine oxidase (XO), and carbonic anhydrase (CA) inhibition. Due to presence of various phytoactive constituents in T. triquetra and inhibitory potential against DPPH, tyrosinase, XO, and CA it may be recommended as a plant of phytopharmaceutical importance.
英文关键词	carbonic anhydrase DPPH GC-MS analysis Trianthema triquetra tyrosinase xanthine oxidase
类型	Article
语种	英语
国家	Pakistan
收录类别	SCI-E
WOS记录号	WOS:000472899800016
WOS关键词	ANTIBACTERIAL ; ESTERS ; ACID
WOS类目	Pharmacology & Pharmacy
WOS研究方向	Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/217502
作者单位	1.Islamia Univ Bahawalpur, Dept Pharm, Bahawalpur 63100, Pakistan; 2.Islamia Univ Bahawalpur, Univ Coll Convent Med, Bahawalpur 63100, Pakistan
推荐引用方式 GB/T 7714	Khurshid, Umair,Ahmad, Saeed,Rehman, Tayyeba,et al. GC-MS Analysis, DPPH & Enzyme Inhibition Assays of Trianthema triquetra Rottl. and Willd. Growing in Pakistan[J],2019,38(6):1181-1187.
APA	Khurshid, Umair,Ahmad, Saeed,Rehman, Tayyeba,Arshad, Muhammad A.,Pervaiz, Irfan,&Saba, Sahar.(2019).GC-MS Analysis, DPPH & Enzyme Inhibition Assays of Trianthema triquetra Rottl. and Willd. Growing in Pakistan.LATIN AMERICAN JOURNAL OF PHARMACY,38(6),1181-1187.
MLA	Khurshid, Umair,et al."GC-MS Analysis, DPPH & Enzyme Inhibition Assays of Trianthema triquetra Rottl. and Willd. Growing in Pakistan".LATIN AMERICAN JOURNAL OF PHARMACY 38.6(2019):1181-1187.