干旱区生态环境知识资源中心(Arid): An extracellular matrix graft (Oasis (R) wound matrix) for treating full-thickness pressure ulcers: A randomized clinical trial

Arid

DOI	10.1016/j.jtv.2018.11.001
	An extracellular matrix graft (Oasis (R) wound matrix) for treating full-thickness pressure ulcers: A randomized clinical trial
	Brown-Etris, Marie 1; Milne, Catherine T.2; Hodde, Jason P.3
通讯作者	Hodde, Jason P.
来源期刊	JOURNAL OF TISSUE VIABILITY
ISSN	0965-206X
出版年	2019
卷号	28 期号:1 页码:21-26
英文摘要	Aim: The purpose of the study was to evaluate clinical safety and effectiveness of Oasis (R) Wound Matrix as a treatment for full-thickness pressure ulcers and compare it to Standard Care. Methods: A total of 130 adults with Stage III or Stage IV pressure ulcers were randomly assigned, received either multiple topical treatments of SIS plus standard care (n = 67), or standard care alone (n = 63), and were subsequently evaluated. Ulcer size was determined at enrollment and weekly throughout treatment. Healing was assessed at each visit for a period of up to 12 weeks, with incidence of complete healing and 90% reduction in ulcer area being the primary outcome measures. Results: The proportion of complete healing in the RS group was 40% as compared to 29% in the standard of care group (p = 0.111); the percentage of patients having a 90% reduction in ulcer surface area was 55% in the SIS group versus 38% in the standard of care group (p = 0.037). Conclusions: The results of this study suggest that within the setting of a comprehensive wound care program, weekly treatment of chronic pressure ulcers with SIS wound matrix increases the incidence of 90% reduction in wound size versus standard of care alone.
英文关键词	Pressure ulcer Extracellular matrix SIS Oasis wound matrix Pressure injury Decubitus ulcer
类型	Article
语种	英语
国家	USA
开放获取类型	hybrid
收录类别	SCI-E ; SSCI
WOS记录号	WOS:000461535300004
WOS关键词	SMALL-INTESTINAL SUBMUCOSA ; LEG ULCERS ; IMPACT
WOS类目	Dermatology ; Nursing
WOS研究方向	Dermatology ; Nursing
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/217399
作者单位	1.Etris Associates Inc, 14450 Bustleton Ave, Philadelphia, PA 19116 USA; 2.Connecticut Clin Nursing Associates LLC, 204 Keegan Rd, Plymouth, CT 06782 USA; 3.Cook Biotech Inc, 1425 Innovat Pl, W Lafayette, IN 47906 USA
推荐引用方式 GB/T 7714	Brown-Etris, Marie,Milne, Catherine T.,Hodde, Jason P.. An extracellular matrix graft (Oasis (R) wound matrix) for treating full-thickness pressure ulcers: A randomized clinical trial[J],2019,28(1):21-26.
APA	Brown-Etris, Marie,Milne, Catherine T.,&Hodde, Jason P..(2019).An extracellular matrix graft (Oasis (R) wound matrix) for treating full-thickness pressure ulcers: A randomized clinical trial.JOURNAL OF TISSUE VIABILITY,28(1),21-26.
MLA	Brown-Etris, Marie,et al."An extracellular matrix graft (Oasis (R) wound matrix) for treating full-thickness pressure ulcers: A randomized clinical trial".JOURNAL OF TISSUE VIABILITY 28.1(2019):21-26.