Knowledge Resource Center for Ecological Environment in Arid Area
| DOI | 10.1007/s12041-019-1134-x |
| Comparative analysis of camelid mitochondrial genomes | |
| Manee, Manee M.1,2; Alshehri, Manal A.1; Binghadir, Sarah A.1; Aldhafer, Shahad H.3; Alswailem, Riyof M.3; Algarni, Abdulmalek T.1; AL-Shomrani, Badr M.1; AL-Fageeh, Mohamed B.1 | |
| 通讯作者 | Manee, Manee M. |
| 来源期刊 | JOURNAL OF GENETICS
 |
| ISSN | 0022-1333 |
| EISSN | 0973-7731 |
| 出版年 | 2019 |
| 卷号 | 98期号:3 |
| 英文摘要 | Camelus dromedarius has played a pivotal role in both culture and way of life in the Arabian peninsula, particularly in arid regions where other domestic animals cannot be easily domesticated. Although, the mitochondrial genomes have recently been sequenced for several camelid species, wider phylogenetic studies are yet to be performed. The features of conserved gene elements, rapid evolutionary rate, and rare recombination make the mitochondrial genome a useful molecular marker for phylogenetic studies of closely related species. Here we carried out a comparative analysis of previously sequenced mitochondrial genomes of camelids with an emphasis on C. dromedarius, revealing a number of noticeable findings. First, the arrangement of mitochondrial genes in C. dromedarius is similar to those of the other camelids. Second, multiple sequence alignment of intergenic regions shows up to 90% similarity across different kinds of camels, with dromedary camels to reach 99%. Third, we successfully identified the three domains (termination-associated sequence, conserved domain and conserved sequence block) of the control region structure. The phylogenetic tree analysis showed that C. dromedarius mitogenomes were significantly clustered in the same clade with Lama pacos mitogenome. These findings will enhance our understanding of the nucleotide composition and molecular evolution of the mitogenomes of the genus Camelus, and provide more data for comparative mitogenomics in the family Camelidae. |
| 英文关键词 | mitochondrial DNA genome annotation phylogenetic analysis control region intergenic regions Camelus dromedarius |
| 类型 | Article |
| 语种 | 英语 |
| 国家 | Saudi Arabia |
| 收录类别 | SCI-E |
| WOS记录号 | WOS:000483708300002 |
| WOS关键词 | PHYLOGENETIC ANALYSIS ; CONTROL REGION ; DNA ; SEQUENCE ; EVOLUTION |
| WOS类目 | Genetics & Heredity |
| WOS研究方向 | Genetics & Heredity |
| 资源类型 | 期刊论文 |
| 条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/217026 |
| 作者单位 | 1.King Abdulaziz City Sci & Technol, Natl Ctr Biotechnol, Riyadh 11442, Saudi Arabia; 2.King Abdulaziz City Sci & Technol, Ctr Excellence Genom, Riyadh 11442, Saudi Arabia; 3.Imam Muhammad Ibn Saud Islamic Univ, Coll Comp & Informat Sci, Riyadh 11432, Saudi Arabia |
| 推荐引用方式 GB/T 7714 | Manee, Manee M.,Alshehri, Manal A.,Binghadir, Sarah A.,et al. Comparative analysis of camelid mitochondrial genomes[J],2019,98(3). |
| APA | Manee, Manee M..,Alshehri, Manal A..,Binghadir, Sarah A..,Aldhafer, Shahad H..,Alswailem, Riyof M..,...&AL-Fageeh, Mohamed B..(2019).Comparative analysis of camelid mitochondrial genomes.JOURNAL OF GENETICS,98(3). |
| MLA | Manee, Manee M.,et al."Comparative analysis of camelid mitochondrial genomes".JOURNAL OF GENETICS 98.3(2019). |
| 条目包含的文件 | 条目无相关文件。 | |||||
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