干旱区生态环境知识资源中心(Arid): Severity of illness assessment with application of the APACHE IV predicted mortality and outcome trends analysis in an academic cardiac intensive care unit

Arid

DOI	10.1016/j.jcrc.2018.12.012
	Severity of illness assessment with application of the APACHE IV predicted mortality and outcome trends analysis in an academic cardiac intensive care unit
	Bennett, Courtney E.1,2; Wright, R. Scott 1; Jentzer, Jacob 1,2; Gajic, Ognjen 2; Murphree, Dennis H.3; Murphy, Joseph G.1; Mankad, Sunil V.1; Wiley, Brandon M.1; Bell, Malcolm R.1; Barsness, Gregory W.1
通讯作者	Bennett, Courtney E.
来源期刊	JOURNAL OF CRITICAL CARE
ISSN	0883-9441
EISSN	1557-8615
出版年	2019
卷号	50 页码:242-246
英文摘要	Purpose: To assess trends in life support interventions and performance of the automated Acute Physiology and Chronic Health Evaluation (APACHE) IV model at mortality prediction compared with Oxford Acute Severity of Illness Score (OASIS) in a contemporary cardiac intensive care unit (CICU). Methods and materials: Retrospective analysis of adults (age >= 18 years) admitted to CICU from January 1, 2007, through December 31, 2015. Temporal trends were assessed with linear regression. Discrimination of each risk score for hospital mortality was assessed with use of area under the receiver operating characteristic curve (AUROC) values. Calibration was assessed with Hosmer-Lemeshow goodness-of-fit test. Results: The study analyzed 10,004 patients. CICU and hospital mortality rates were 5.7% and 9.1%. APACHE IV predicted death had an AUROC of 0.82 (0.81-0.84) for hospital death, compared with 0.79 for OASIS (P < .05). Calibration was better for OASIS than APACHE IV. Increases were observed in CICU and hospital lengths of stay (both P < .001), APACHE IV predicted mortality (P = .007), Charlson Comorbidity Index (P < .001), noninvasive ventilation use (P < .001), and noninvasive ventilation days (P = .02). Conclusions: Contemporary CICU patients are increasingly ill, observed in upward trends in comorbid conditions and life support interventions. APACHE IV predicted death and OASIS showed good discrimination in predicting death in this population. APACHE IV and OASIS may be useful for benchmarking and quality improvement initiatives in the CICU, the former having better discrimination. (C) 2018 Elsevier Inc. All rights reserved.
英文关键词	Comorbidity Critical care Mortality Quality improvement Renal replacement therapy Ventilation
类型	Article
语种	英语
国家	USA
开放获取类型	Green Accepted
收录类别	SCI-E
WOS记录号	WOS:000458375800037
WOS关键词	HOSPITAL MORTALITY ; ACUTE PHYSIOLOGY ; CORONARY ; EXPERIENCE ; EVOLUTION
WOS类目	Critical Care Medicine
WOS研究方向	General & Internal Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/216900
作者单位	1.Mayo Clin, Dept Cardiovasc Med, 200 First St SW, Rochester, MN 55905 USA; 2.Mayo Clin, Div Pulm & Crit Care Med, Rochester, MN USA; 3.Mayo Clin, Div Biomed Stat & Informat, Rochester, MN USA
推荐引用方式 GB/T 7714	Bennett, Courtney E.,Wright, R. Scott,Jentzer, Jacob,et al. Severity of illness assessment with application of the APACHE IV predicted mortality and outcome trends analysis in an academic cardiac intensive care unit[J],2019,50:242-246.
APA	Bennett, Courtney E..,Wright, R. Scott.,Jentzer, Jacob.,Gajic, Ognjen.,Murphree, Dennis H..,...&Barsness, Gregory W..(2019).Severity of illness assessment with application of the APACHE IV predicted mortality and outcome trends analysis in an academic cardiac intensive care unit.JOURNAL OF CRITICAL CARE,50,242-246.
MLA	Bennett, Courtney E.,et al."Severity of illness assessment with application of the APACHE IV predicted mortality and outcome trends analysis in an academic cardiac intensive care unit".JOURNAL OF CRITICAL CARE 50(2019):242-246.