干旱区生态环境知识资源中心(Arid): The dromedary camel displays annual variation in hypothalamic kisspeptin and Arg-Phe-amide-related peptide-3 according to sex, season, and breeding activity

Arid

DOI	10.1002/cne.24736
	The dromedary camel displays annual variation in hypothalamic kisspeptin and Arg-Phe-amide-related peptide-3 according to sex, season, and breeding activity
	Ainani, Hassan 1,2; El Bousmaki, Najlae 1; Poirel, Vincent-Joseph 2; Achaaban, Mohamed Rachid 1; Ouassat, Mohammed 1; Piro, Mohammed 3; Klosen, Paul 2; Simonneaux, Valerie 2; El Allali, Khalid 1
通讯作者	El Allali, Khalid
来源期刊	JOURNAL OF COMPARATIVE NEUROLOGY
ISSN	0021-9967
EISSN	1096-9861
出版年	2020
卷号	528 期号:1 页码:32-47
英文摘要	The dromedary camel (Camelus dromedarius) is a desert mammal whose cycles in reproductive activity ensure that the offspring's birth and weaning coincide with periods of abundant food resources and favorable climate conditions. In this study, we assessed whether kisspeptin (Kp) and arginine-phenylalanine (RF)-amide related peptide-3 (RFRP-3), two hypothalamic peptides known to regulate the mammalian hypothalamo-pituitary gonadal axis, may be involved in the seasonal control of camel's reproduction. Using specific antibodies and riboprobes, we found that Kp neurons are present in the preoptic area (POA), suprachiasmatic (SCN), and arcuate (ARC) nuclei, and that RFRP-3 neurons are present in the paraventricular (PVN), dorsomedial (DMH), and ventromedial (VMH) hypothalamic nuclei. Kp fibers are found in various hypothalamic areas, notably the POA, SCN, PVN, DMH, VMH, supraoptic nucleus, and the ventral and dorsal premammillary nucleus. RFRP-3 fibers are found in the POA, SCN, PVN, DMH, VMH, and ARC. POA and ARC Kp neurons and DMH RFRP-3 neurons display sexual dimorphism with more neurons in female than in male. Both neuronal populations display opposed seasonal variations with more Kp neurons and less RFRP-3 neurons during the breeding (December-January) than the nonbreeding (July-August) season. This study is the first describing Kp and RFRP-3 in the camel's brain with, during the winter period lower RFRP-3 expression and higher Kp expression possibly responsible for the HPG axis activation. Altogether, our data indicate the involvement of both Kp and RFRP-3 in the seasonal control of the dromedary camel's breeding activity.
英文关键词	Dromedary camel kisspeptin RFRP-3 RRID:AB_2340593 RRID:AB_258649 RRID:AB_514497 RRID:SCR_001935 RRID:SCR_002677 seasonal breeding
类型	Article
语种	英语
国家	Morocco ; France
收录类别	SCI-E
WOS记录号	WOS:000477403100001
WOS关键词	GONADOTROPIN-RELEASING-HORMONE ; RFAMIDE-RELATED PEPTIDE ; RIBONUCLEIC-ACID EXPRESSION ; KISS1 GENE-EXPRESSION ; HUMAN-BRAIN ; SUPRACHIASMATIC NUCLEUS ; ARCUATE NUCLEUS ; MESSENGER-RNA ; PREOPTIC AREA ; CDNA CLONING
WOS类目	Neurosciences ; Zoology
WOS研究方向	Neurosciences & Neurology ; Zoology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/216890
作者单位	1.Hassan II Agron & Vet Inst, Rabat Inst, Comparat Anat Unit, Rabat, Morocco; 2.Univ Strasbourg, CNRS UPR 3212, Inst Cellular & Integrat Neurosci, Strasbourg, France; 3.Hassan II Agron & Vet Inst, Rabat Inst, Med & Surg Unit Domest Anim, Rabat, Morocco
推荐引用方式 GB/T 7714	Ainani, Hassan,El Bousmaki, Najlae,Poirel, Vincent-Joseph,et al. The dromedary camel displays annual variation in hypothalamic kisspeptin and Arg-Phe-amide-related peptide-3 according to sex, season, and breeding activity[J],2020,528(1):32-47.
APA	Ainani, Hassan.,El Bousmaki, Najlae.,Poirel, Vincent-Joseph.,Achaaban, Mohamed Rachid.,Ouassat, Mohammed.,...&El Allali, Khalid.(2020).The dromedary camel displays annual variation in hypothalamic kisspeptin and Arg-Phe-amide-related peptide-3 according to sex, season, and breeding activity.JOURNAL OF COMPARATIVE NEUROLOGY,528(1),32-47.
MLA	Ainani, Hassan,et al."The dromedary camel displays annual variation in hypothalamic kisspeptin and Arg-Phe-amide-related peptide-3 according to sex, season, and breeding activity".JOURNAL OF COMPARATIVE NEUROLOGY 528.1(2020):32-47.