干旱区生态环境知识资源中心(Arid): The paleoepidemiology of Sacral Spina Bifida Occulta in population samples from the Dakhleh Oasis, Egypt

Arid

DOI	10.1016/j.ijpp.2019.06.006
	The paleoepidemiology of Sacral Spina Bifida Occulta in population samples from the Dakhleh Oasis, Egypt
	Molto, Joseph E.; Kirkpatrick, Casey L.; Keron, James
通讯作者	Molto, Joseph E.
来源期刊	INTERNATIONAL JOURNAL OF PALEOPATHOLOGY
ISSN	1879-9817
EISSN	1879-9825
出版年	2019
卷号	26 页码:93-103
英文摘要	Objective: To document sacral spina bifida occulta (SSB0) prevalence in a population sample from the Dakhleh Oasis, Egypt, and address methodological issues in recording and quantifying SSBO variations. Materials: 442 adult sacra from two temporally disjunct samples from the same deme traversing the 3rd intermediate (TIP) and the Roman Periods. Methods: Sacra were scored for SSBO, excluding the sacral hiatus. Risk of SSBO was calculated with the common odds ratio and statistical significance by X-2. Data were compared to other archaeological SSBO data. Results: SSBO was present in 15.6% of the sample with a slight, but not significant, temporal increase (TIP to Roman Period) in males, and a significant age-correlated increase in both sexes. Most open sacra occurred in young adults. Conclusions: Data support that SSBO can be considered as a morphogenetic variant. Dakhleh data fall within the prevalence range for most populations, however inter-population comparisons are complicated by methodological inconsistencies. Significance: SSBO can be used in paleogenetic research. Limitations: Methodological differences in scoring SSBO prevent effective comparative study. Suggested future research: Future studies require more rigorous and standardized scoring methods. aDNA may be used to corroborate the morphogenetic value of SSBO and determine its clinical significance.
英文关键词	Congenital Morphogenetic Morbidity Odds ratio Sacral clefting
类型	Article
语种	英语
国家	Canada
收录类别	SCI-E ; SSCI
WOS记录号	WOS:000481623700011
WOS关键词	VERTEBRAL COLUMN ; CORD SYNDROME ; RISK-FACTORS ; PREVALENCE ; EXPRESSION ; GENETICS ; DEFECTS ; FOLATE ; GENES ; AGE
WOS类目	Paleontology ; Pathology
WOS研究方向	Paleontology ; Pathology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/216482
作者单位	Univ Western Univ, Dept Anthropol, London, ON, Canada
推荐引用方式 GB/T 7714	Molto, Joseph E.,Kirkpatrick, Casey L.,Keron, James. The paleoepidemiology of Sacral Spina Bifida Occulta in population samples from the Dakhleh Oasis, Egypt[J],2019,26:93-103.
APA	Molto, Joseph E.,Kirkpatrick, Casey L.,&Keron, James.(2019).The paleoepidemiology of Sacral Spina Bifida Occulta in population samples from the Dakhleh Oasis, Egypt.INTERNATIONAL JOURNAL OF PALEOPATHOLOGY,26,93-103.
MLA	Molto, Joseph E.,et al."The paleoepidemiology of Sacral Spina Bifida Occulta in population samples from the Dakhleh Oasis, Egypt".INTERNATIONAL JOURNAL OF PALEOPATHOLOGY 26(2019):93-103.