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DOI | 10.3389/fendo.2019.00064 |
Regulation of Feeding and Metabolism by Neuropeptide F and Short Neuropeptide F in Invertebrates | |
Fadda, Melissa; Hasakiogullari, Ilayda; Temmerman, Liesbet; Beets, Isabel; Zels, Sven; Schoofs, Liliane | |
通讯作者 | Schoofs, Liliane |
来源期刊 | FRONTIERS IN ENDOCRINOLOGY
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ISSN | 1664-2392 |
出版年 | 2019 |
卷号 | 10 |
英文摘要 | Numerous neuropeptide systems have been implicated to coordinately control energy homeostasis, both centrally and peripherally. However, the vertebrate neuropeptide Y (NPY) system has emerged as the best described one regarding this biological process. The protostomian ortholog of NPY is neuropeptide F, characterized by an RXRF(Y) amide carboxyterminal motif. A second neuropeptide system is short NPF, characterized by an M/T/L/FRF(W) amide carboxyterminal motif. Although both short and long NPF neuropeptide systems display carboxyterminal sequence similarities, they are evolutionary distant and likely already arose as separate signaling systems in the common ancestor of deuterostomes and protostomes, indicating the functional importance of both. Both NPF and short-NPF systems seem to have roles in the coordination of feeding across bilaterian species, but during chordate evolution, the short NPF system appears to have been lost or evolved into the prolactin releasing peptide signaling system, which regulates feeding and has been suggested to be orthologous to sNPF. Here we review the roles of both NPF and sNPF systems in the regulation of feeding and metabolism in invertebrates. |
英文关键词 | neuropeptide F neuropeptide Y short neuropeptide F feeding behavior neuropeptide evolution G protein coupled receptor protostomes neuromodulation |
类型 | Review |
语种 | 英语 |
国家 | Belgium |
开放获取类型 | Green Published, gold |
收录类别 | SCI-E |
WOS记录号 | WOS:000459106400001 |
WOS关键词 | FMRFAMIDE-LIKE NEUROPEPTIDES ; PROTEIN-COUPLED RECEPTOR ; CENTRAL-NERVOUS-SYSTEM ; CAENORHABDITIS-ELEGANS ; Y-LIKE ; PEPTIDE-YY ; IMMUNOCYTOCHEMICAL DEMONSTRATION ; GENE-EXPRESSION ; DESERT LOCUST ; FOOD-INTAKE |
WOS类目 | Endocrinology & Metabolism |
WOS研究方向 | Endocrinology & Metabolism |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/215763 |
作者单位 | Katholieke Univ Leuven, Dept Biol Funct Genom & Prote, Leuven, Belgium |
推荐引用方式 GB/T 7714 | Fadda, Melissa,Hasakiogullari, Ilayda,Temmerman, Liesbet,et al. Regulation of Feeding and Metabolism by Neuropeptide F and Short Neuropeptide F in Invertebrates[J],2019,10. |
APA | Fadda, Melissa,Hasakiogullari, Ilayda,Temmerman, Liesbet,Beets, Isabel,Zels, Sven,&Schoofs, Liliane.(2019).Regulation of Feeding and Metabolism by Neuropeptide F and Short Neuropeptide F in Invertebrates.FRONTIERS IN ENDOCRINOLOGY,10. |
MLA | Fadda, Melissa,et al."Regulation of Feeding and Metabolism by Neuropeptide F and Short Neuropeptide F in Invertebrates".FRONTIERS IN ENDOCRINOLOGY 10(2019). |
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