干旱区生态环境知识资源中心(Arid): A possible role of biogenic silica in esophageal cancer in North China?

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DOI	10.1007/s11356-019-04332-w
	A possible role of biogenic silica in esophageal cancer in North China?
	Lian, Changhong 1; Zuo, Xinxin 2; Tian, Linwei 3
通讯作者	Tian, Linwei
来源期刊	ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
ISSN	0944-1344
EISSN	1614-7499
出版年	2019
卷号	26 期号:8 页码:8340-8343
英文摘要	Certain areas in North China have the highest incidence of esophageal squamous cell carcinoma (ESCC) in the world, which has not seen convincing explanation by any risk factor yet. Biogenic silica in millet bran was linked to ESCC in the early 1980s but the hypothesis was largely dismissed because of the lack of geographic correlation between millet consumption and ESCC. Later epidemiological studies disclosed the linkage of wheat consumption in North China to ESCC instead. Now, we hypothesize silica phytoliths (silicified bodies that have definite shapes) from wheat chaff are a major etiologic factor of ESCC in this region. This hypothesis is supported by the potentially high abundance of silica phytoliths on the bracts of wheat (Triticum aestivum) in North China due to favorable Si-accumulation genotype, arid climate, and siallitic soil with bioavailable Si. These silica phytoliths can contaminate wheat flour and cause repeated local injuries in the esophagus and stimulate proliferation by providing anchorage.
英文关键词	Environmental geochemistry Esophageal squamous cell carcinoma (ESCC) Biogenic silica Wheat chaff Silica phytolith Siallitic soil Aridity
类型	Article
语种	英语
国家	Peoples R China
收录类别	SCI-E
WOS记录号	WOS:000463824600090
WOS关键词	WHEAT TRITICUM-AESTIVUM ; INFLORESCENCE BRACTS ; PHYTOLITHS ; DEPOSITION ; L.
WOS类目	Environmental Sciences
WOS研究方向	Environmental Sciences & Ecology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/215538
作者单位	1.Changzhi Med Coll, Heping Hosp, Dept Surg Oncol, Changzhi, Peoples R China; 2.Fujian Normal Univ, Coll Geogroph Sci, State Key Lab Subtrop Mt Ecol, Fuzhou, Fujian, Peoples R China; 3.Univ Hong Kong, Sch Publ Hlth, 7 Sassoon Rd, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Lian, Changhong,Zuo, Xinxin,Tian, Linwei. A possible role of biogenic silica in esophageal cancer in North China?[J],2019,26(8):8340-8343.
APA	Lian, Changhong,Zuo, Xinxin,&Tian, Linwei.(2019).A possible role of biogenic silica in esophageal cancer in North China?.ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,26(8),8340-8343.
MLA	Lian, Changhong,et al."A possible role of biogenic silica in esophageal cancer in North China?".ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH 26.8(2019):8340-8343.