Arid
DOI10.1111/echo.14242
Nonlinear model for the carotid artery disease 10-year risk prediction by fusing conventional cardiovascular factors to carotid ultrasound image phenotypes: A Japanese diabetes cohort study
Khanna, Narendra N.1; Jamthikar, Ankush D.2; Araki, Tadashi3; Gupta, Deep2; Piga, Matteo4,5; Saba, Luca6; Carcassi, Carlo7; Nicolaides, Andrew8,9; Laird, John R.10; Suri, Harman S.11; Gupta, Ajay12,13; Mavrogeni, Sophie14; Kitas, George D.15,16; Suri, Jasjit S.17
通讯作者Suri, Jasjit S.
来源期刊ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
ISSN0742-2822
EISSN1540-8175
出版年2019
卷号36期号:2页码:345-361
英文摘要Motivation; This study presents a novel nonlinear model Which can Predict 10-Year carotid ultrasound image-based phenotypes by fusing nine traditional cardiovascular risk factors (ethnicity, gender, age, artery type, body mass index, hemoglobin Alc, hypertension, low-density lipoprotein, and smoking) with five types of carotid automated image phenotypes (three types of carotid intima-media thickness (IMT), wall variability, and total plaque area). Methodology: Two-step process was adapted: First, five baseline carotid irnage-based phenotypes were automatically measured using AtheroEdge (TM) (AtheroPoint (TM), CA, USA) system by two operators (novice arid experienced) and an expert. Second, based on the annual progression rates of clMT due to nine traditional cardiovascular risk factors, a novel nonlinear model was adapted for 10-year predictions of carotid phenotypes. Results: Institute review board (IRB) approved 204 Japanese patients' left/right common carotid artery (407 ultrasound scans) was collected with a mean age of 69 +/- 11 years. Age and hemoglobin were reported to have a high influence on the 10-year carotid phenotypes. Mean correlation coefficient (CC) between 10-year carotid image-based phenotype and age was improved by 39.35% in males and 25.38% in females. The area under the curves for the 10-year measurements of five phenotypes IMTave10yr, IMTmax(10yr), IMTmin10yr, IMTV10yr, and TPA(10yr) were 0.96, 0.94, 0.90, 1.0, and 1.0. Inter-operator variability between two operators showed significant CC (P < 0.0001). Conclusions: A nonlinear model was developed and validated by fusing nine conventional CV risk factors with current carotid image-based phenotypes for predicting the 10-year carotid ultrasound image-based phenotypes which may be used risk assessment.
英文关键词10-year risk prediction atherosclerosis carotid intima-media thickness nonlinear modeling stroke total plaque area traditional cardiovascular risk ultrasound
类型Article
语种英语
国家India ; Japan ; Italy ; England ; Cyprus ; USA ; Greece
开放获取类型Green Submitted
收录类别SCI-E
WOS记录号WOS:000458874600018
WOS关键词INTIMA-MEDIA THICKNESS ; CORONARY-HEART-DISEASE ; BLOOD-PRESSURE ; IMT MEASUREMENT ; ATHEROSCLEROSIS RISK ; STROKE RISK ; SUBCLINICAL ATHEROSCLEROSIS ; CIGARETTE-SMOKING ; VARIABILITY IMTV ; YOUNG ADULTHOOD
WOS类目Cardiac & Cardiovascular Systems
WOS研究方向Cardiovascular System & Cardiology
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/215118
作者单位1.Indraprastha Apollo Hosp, Dept Cardiol, New Delhi, India;
2.Visvesvaraya Natl Inst Technol, Dept Elect & Commun Engn, Nagpur, Maharashtra, India;
3.Toho Univ, Ohashi Med Ctr, Div Cardiovasc Med, Tokyo, Japan;
4.Univ Clin, Dept Rheumatol, Cagliari, Italy;
5.AOU Cagliari, Cagliari, Italy;
6.Univ Cagliari, Dept Radiol, Cagliari, Italy;
7.Univ Cagliari, Dept Genet, Cagliari, Italy;
8.Imperial Coll, Dept Vasc Surg, London, England;
9.Univ Cyprus, Vasc Diagnost Ctr, Nicosia, Cyprus;
10.Adventist Hlth St Helena, Heart & Vasc Inst, St Helena, CA USA;
11.Brown Univ, Providence, RI 02912 USA;
12.Weill Cornell Med Ctr, Dept Radiol, New York, NY USA;
13.Weill Cornell Med Ctr, Feil Family Brain & Mind Res Inst, New York, NY USA;
14.Onassis Cardiac Surg Ctr, Cardiol Clin, Athens, Greece;
15.Univ Manchester, Arthrit Res UK Ctr Epidemiol, Manchester, Lancs, England;
16.Dudley Grp NHS Fdn Trust, Res & Dev Acad Affairs, Dudley, England;
17.AtheroPoint, Stroke Monitoring & Diagnost Div, Roseville, CA USA
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Khanna, Narendra N.,Jamthikar, Ankush D.,Araki, Tadashi,et al. Nonlinear model for the carotid artery disease 10-year risk prediction by fusing conventional cardiovascular factors to carotid ultrasound image phenotypes: A Japanese diabetes cohort study[J],2019,36(2):345-361.
APA Khanna, Narendra N..,Jamthikar, Ankush D..,Araki, Tadashi.,Gupta, Deep.,Piga, Matteo.,...&Suri, Jasjit S..(2019).Nonlinear model for the carotid artery disease 10-year risk prediction by fusing conventional cardiovascular factors to carotid ultrasound image phenotypes: A Japanese diabetes cohort study.ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES,36(2),345-361.
MLA Khanna, Narendra N.,et al."Nonlinear model for the carotid artery disease 10-year risk prediction by fusing conventional cardiovascular factors to carotid ultrasound image phenotypes: A Japanese diabetes cohort study".ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES 36.2(2019):345-361.
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