Arid
DOI10.1158/1078-0432.CCR-19-0188
Tumor Landscapes: beta-Catenin Drives Immune Desertification
Dangaj, Denarda; Barras, David; Coukos, George
通讯作者Coukos, George
来源期刊CLINICAL CANCER RESEARCH
ISSN1078-0432
EISSN1557-3265
出版年2019
卷号25期号:10页码:2943-2945
英文摘要Immune checkpoint blockade therapy requires a preestablished activated immune landscape. Understanding tumor-intrinsic mechanisms that lead to T-cell desertification is key to resensitizing them to such therapies. The WNT/beta-catenin tumor-intrinsic signaling is emerging as an immune exclusion pathway that holds high promise to counteract resistance to immunotherapy.
类型Editorial Material
语种英语
国家Switzerland
开放获取类型Bronze
收录类别SCI-E
WOS记录号WOS:000468064200001
WOS类目Oncology
WOS研究方向Oncology
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/214929
作者单位(1)Univ Lausanne, Ludwig Inst Canc Res, Lausanne Univ Hosp, Lausanne, Switzerland;(2)Univ Lausanne, Dept Oncol, Lausanne Univ Hosp, Lausanne, Switzerland
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GB/T 7714
Dangaj, Denarda,Barras, David,Coukos, George. Tumor Landscapes: beta-Catenin Drives Immune Desertification[J],2019,25(10):2943-2945.
APA Dangaj, Denarda,Barras, David,&Coukos, George.(2019).Tumor Landscapes: beta-Catenin Drives Immune Desertification.CLINICAL CANCER RESEARCH,25(10),2943-2945.
MLA Dangaj, Denarda,et al."Tumor Landscapes: beta-Catenin Drives Immune Desertification".CLINICAL CANCER RESEARCH 25.10(2019):2943-2945.
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