干旱区生态环境知识资源中心(Arid): Exploring a multi-exposure-pathway approach to assess human health risk associated with groundwater fluoride exposure in the semi-arid region of east India

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DOI	10.1016/j.chemosphere.2019.05.278
	Exploring a multi-exposure-pathway approach to assess human health risk associated with groundwater fluoride exposure in the semi-arid region of east India
	Mukherjee, Indrani 1; Singh, Umesh Kumar 1; Patra, Pulak Kumar 2
通讯作者	Singh, Umesh Kumar
来源期刊	CHEMOSPHERE
ISSN	0045-6535
EISSN	1879-1298
出版年	2019
卷号	233 页码:164-173
英文摘要	Human health risks associated with groundwater fluoride have been assessed using USEPA method in few parts of India, but those assessments were conducted based on a single value for each parameter, which may lead to certain inaccuracy and uncertainties in results. In this study, a higher degree of accuracy in health risk assessment was achieved through Monte Carlo simulations, sensitivity analysis and uncertainty analysis. As fluoride hazards to human health are chronic, a total of 4560 water samples (N = 4560) were collected during consecutive four seasons (2 pre-monsoon and 2 post-monsoon seasons; 1140 samples/season) from the entire Birbhum district, covering all the blocks and geological settings to obtain the spatiotemporal variation of fluoride level. The Empirical Bayesian Kriging geo-statistical model was employed to determine fluoride endemic areas. Amongst all blocks, Nalhati-1 had exhibited the highest fluoride level (18.25 mg/L). The study revealed that most of the blocks are vulnerable to groundwater fluoride due to its occurrences in excess level. The average and 95th percentile values of total hazard index indicate that the infants and children populations of the district are more susceptible than the adults and teens. The sensitivity analysis revealed that water ingestion rate and fluoride concentration are the most influential parameters for higher risk of fluoride-related health hazards. Health risks were evaluated through ingestion and dermal exposure routes for infants, children, teens, and adult residents. The exposure was much higher through ingestion than dermal contacts. Ingestion of defluoridated water will reduce the health risks associated with groundwater fluoride exposure. (C) 2019 Elsevier Ltd. All rights reserved.
英文关键词	Fluoride Groundwater Health risk Dermal exposure Uncertainty analysis Monte Carlo simulation
类型	Article
语种	英语
国家	India
收录类别	SCI-E
WOS记录号	WOS:000477691500020
WOS关键词	DRINKING-WATER ; ENDEMIC FLUOROSIS ; DENTAL FLUOROSIS ; BIRBHUM DISTRICT ; WEST-BENGAL
WOS类目	Environmental Sciences
WOS研究方向	Environmental Sciences & Ecology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/214883
作者单位	1.Visva Bharati, ISERC, Inst Sci, Birbhum 731235, W Bengal, India; 2.Visva Bharati, Dept Environm Studies, Inst Sci, Birbhum 731235, W Bengal, India
推荐引用方式 GB/T 7714	Mukherjee, Indrani,Singh, Umesh Kumar,Patra, Pulak Kumar. Exploring a multi-exposure-pathway approach to assess human health risk associated with groundwater fluoride exposure in the semi-arid region of east India[J],2019,233:164-173.
APA	Mukherjee, Indrani,Singh, Umesh Kumar,&Patra, Pulak Kumar.(2019).Exploring a multi-exposure-pathway approach to assess human health risk associated with groundwater fluoride exposure in the semi-arid region of east India.CHEMOSPHERE,233,164-173.
MLA	Mukherjee, Indrani,et al."Exploring a multi-exposure-pathway approach to assess human health risk associated with groundwater fluoride exposure in the semi-arid region of east India".CHEMOSPHERE 233(2019):164-173.