干旱区生态环境知识资源中心(Arid): High-Frequency Fluctuations in Post-stenotic Patient Specific Carotid Stenosis Fluid Dynamics: A Computational Fluid Dynamics Strategy Study

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DOI	10.1007/s13239-019-00410-9
	High-Frequency Fluctuations in Post-stenotic Patient Specific Carotid Stenosis Fluid Dynamics: A Computational Fluid Dynamics Strategy Study
	Mancini, Viviana 1; Bergersen, Aslak W.2; Vierendeels, Jan 3; Segers, Patrick 1; Valen-Sendstad, Kristian 2
通讯作者	Mancini, Viviana
来源期刊	CARDIOVASCULAR ENGINEERING AND TECHNOLOGY
ISSN	1869-408X
EISSN	1869-4098
出版年	2019
卷号	10 期号:2 页码:277-298
英文摘要	PurposeScreening of asymptomatic carotid stenoses is performed by auscultation of the carotid bruit, but the sensitivity is poor. Instead, it has been suggested to detect carotid bruit as neck's skin vibrations. We here take a first step towards a computational fluid dynamics proof-of-concept study, and investigate the robustness of our numerical approach for capturing high-frequent fluctuations in the post-stenotic flow. The aim was to find an ideal solution strategy from a pragmatic point of view, balancing accuracy with computational cost comparing an under-resolved direct numerical simulation (DNS) approach vs. three common large eddy simulation (LES) models (static/dynamic Smagorinsky and Sigma).MethodWe found a reference solution by performing a spatial and temporal refinement study of a stenosed carotid bifurcation with constant flow rate. The reference solution dwas compared against LES for both a constant and pulsatile flow.ResultsOnly the Sigma and Dynamic Smagorinsky models were able to replicate the flow field of the reference solution for a pulsatile simulation, however the computational cost of the Sigma model was lower. However, none of the sub-grid scale models were able to replicate the high-frequent flow in the peak-systolic constant flow rate simulations, which had a higher mean Reynolds number.ConclusionsThe Sigma model was the best combination between accuracy and cost for simulating the pulsatile post-stenotic flow field, whereas for the constant flow rate, the under-resolved DNS approach was better. These results can be used as a reference for future studies investigating high-frequent flow features.
英文关键词	CFD Finite elements Carotid stenosis Oasis LES
类型	Article
语种	英语
国家	Belgium ; Norway
开放获取类型	Green Published, hybrid
收录类别	SCI-E
WOS记录号	WOS:000468445200008
WOS关键词	INTRACRANIAL ANEURYSM HEMODYNAMICS ; DIRECT NUMERICAL-SIMULATION ; TRANSITIONAL FLOW ; IMPACT ; INSTABILITIES ; PLAQUE ; GAP
WOS类目	Cardiac & Cardiovascular Systems ; Engineering, Biomedical
WOS研究方向	Cardiovascular System & Cardiology ; Engineering
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/214794
作者单位	1.Univ Ghent, IBiTech BioMMeda, B-9000 Ghent, Belgium; 2.Simula Res Lab, Dept Computat Physiol, N-1364 Fornebu, Norway; 3.Univ Ghent, Dept Flow Heat & Combust Mech, B-9000 Ghent, Belgium
推荐引用方式 GB/T 7714	Mancini, Viviana,Bergersen, Aslak W.,Vierendeels, Jan,et al. High-Frequency Fluctuations in Post-stenotic Patient Specific Carotid Stenosis Fluid Dynamics: A Computational Fluid Dynamics Strategy Study[J],2019,10(2):277-298.
APA	Mancini, Viviana,Bergersen, Aslak W.,Vierendeels, Jan,Segers, Patrick,&Valen-Sendstad, Kristian.(2019).High-Frequency Fluctuations in Post-stenotic Patient Specific Carotid Stenosis Fluid Dynamics: A Computational Fluid Dynamics Strategy Study.CARDIOVASCULAR ENGINEERING AND TECHNOLOGY,10(2),277-298.
MLA	Mancini, Viviana,et al."High-Frequency Fluctuations in Post-stenotic Patient Specific Carotid Stenosis Fluid Dynamics: A Computational Fluid Dynamics Strategy Study".CARDIOVASCULAR ENGINEERING AND TECHNOLOGY 10.2(2019):277-298.