干旱区生态环境知识资源中心(Arid): A coumarin analogue NFA from endophytic Aspergillus fumigatus improves drought resistance in rice as an antioxidant

Arid

DOI	10.1186/s12866-019-1419-5
	A coumarin analogue NFA from endophytic Aspergillus fumigatus improves drought resistance in rice as an antioxidant
	Qin, Wanggege 1; Liu, Chengxiong 1,2; Jiang, Wei 1,3; Xue, Yanhong 1,2; Wang, Guangxi 3; Liu, Shiping 1,2
通讯作者	Liu, Shiping
来源期刊	BMC MICROBIOLOGY
ISSN	1471-2180
出版年	2019
卷号	19
英文摘要	BackgroundDrought and its resulting oxidative damage are the major yield limiting factors for crops in arid and semi-arid regions. Recent studies have found that endophytic fungi coexisting in plants can alleviate biotic or abiotic damage to plant growth and development. In order to screen for the endophytes associated with drought stress, 12 strains of endophytic fungi with high antioxidant activity isolated from riparian plants Myricaria laxiflora were evaluated for their effects in rice by the crude extracts.ResultsOf the 12 endophytic fungi, Aspergillus fumigatus SG-17 functioned most effectively, with the crude extract exhibiting relatively higher antioxidant capacity both in vivo and in vitro. The subsequent MS and NMR analysis showed that the primary substance responsible for the antioxidant activity in the extract was (Z)-N-(4-hydroxystyryl) formamide (NFA), an analogue of coumarin. Enzyme activity assay in nerve cells SH-SY5Y showed that NFA could maintain the membrane integrity and regulate the antioxidase activity under oxidative stress. In rice suffering drought stress, NFA effectively alleviated the harm by regulating the contents of NADPH oxidases, antioxidants and heat shock proteins, all of which are closely related with the reactive oxygen species pathway.ConclusionThese findings indicated that some endophytes from plants often subjected to flooding and oxidative stress could enhance drought resistance by producing compounds such as NFA to regulate the oxidative pathway.
英文关键词	Endophytic fungus Aspergillus fumigatus NFA Antioxidant Drought stress
类型	Article
语种	英语
国家	Peoples R China ; Japan
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000459871000001
WOS关键词	FUNGAL ENDOPHYTES ; MYRICARIA-LAXIFLORA ; STRESS-RESPONSE ; IN-VITRO ; PLANT ; DIVERSITY ; GROWTH ; ROS ; THERMOTOLERANCE ; PROLIFERATION
WOS类目	Microbiology
WOS研究方向	Microbiology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/214699
作者单位	1.China Three Gorges Univ, Coll Life Sci & Pharm, Yichang 443002, Peoples R China; 2.China Three Gorges Univ, Coll Life Sci & Pharm, Hubei Key Lab Nat Prod Res & Dev, Yichang 443002, Peoples R China; 3.Meijo Univ, Lab Plant Conservat Sci, Fac Agr, Nagoya, Aichi 4688502, Japan
推荐引用方式 GB/T 7714	Qin, Wanggege,Liu, Chengxiong,Jiang, Wei,et al. A coumarin analogue NFA from endophytic Aspergillus fumigatus improves drought resistance in rice as an antioxidant[J],2019,19.
APA	Qin, Wanggege,Liu, Chengxiong,Jiang, Wei,Xue, Yanhong,Wang, Guangxi,&Liu, Shiping.(2019).A coumarin analogue NFA from endophytic Aspergillus fumigatus improves drought resistance in rice as an antioxidant.BMC MICROBIOLOGY,19.
MLA	Qin, Wanggege,et al."A coumarin analogue NFA from endophytic Aspergillus fumigatus improves drought resistance in rice as an antioxidant".BMC MICROBIOLOGY 19(2019).