干旱区生态环境知识资源中心(Arid): Cognitive improvement effects of electro-acupuncture for the treatment of MCI compared with Western medications: a systematic review and Meta-analysis

Arid

DOI	10.1186/s12906-018-2407-2
	Cognitive improvement effects of electro-acupuncture for the treatment of MCI compared with Western medications: a systematic review and Meta-analysis
	Kim, Hwan 1,2; Kim, Hong Kyoung 2,3; Kim, Si Yeon 2; Kim, Young Il 3; Yoo, Ho Ryong 4; Jung, In Chul 1,2
通讯作者	Jung, In Chul
来源期刊	BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE
EISSN	1472-6882
出版年	2019
卷号	19
英文摘要	BackgroundAlmost half of mild cognitive impairment (MCI) patients progress to dementia, which is associated with decreased quality of life and obstacles to independent living. Relevant management is expected to prevent MCI patients from progressing to dementia. In recent years, electroacupuncture (EA) has been used to treat various kinds of neurological disorders including MCI. This study evaluates the use of EA for MCI patients to increase cognitive function through a comparison with Western medications.MethodsRandomized controlled trials (RCT) or systematical reviews (SR) of EA versus Western medications for MCI were searched using the following 10 databases: Pubmed, Cochrane Library, CINAHL, EMBASE, China National Knowledge Infrastructure (CNKI), National Digital Science Library (NDSL), Journal of Oriental Neuropsychiatry (JON), Korean Medical Database (KMBASE), KoreaMed, and OASIS, from October 2007 to August 2017, without language restriction. A methodological quality assessment of RCTs or SRs that met inclusion criteria was conducted using Cochrane Risk of bias (RoB) tool and a meta-analysis by RevMan (Review Manager) 5.3.5 version of Cochrane collaboration.ResultsFive RCTs with 257 patients met inclusion criteria and those were randomly divided into two groups: the EA group (n=103) and Western medications group (n=154). The methodological quality of the included studies showed high risk or/and unclear of risk of bias. The meta-analysis of five studies reported that the EA group was better than the Western medications group, improving the Mini Mental State Examination (MMSE) score by 0.65 [95% CI 0.28 similar to 1.01] higher mean difference, Montreal Cognitive Assessment (MoCA) score by 0.66 [95% CI 0.00 similar to 1.32] higher mean difference. Adverse effects were not reported in the selected studies.ConclusionElectroacupuncture was an effective treatment for MCI patients by improving cognitive function. However, the included studies presented a low methodological quality and no adverse effects were reported. Thus, further comprehensive studies with a design in depth are needed to derive significant results.
英文关键词	Mild cognitive impairment (MCI) Electroacupuncture (EA) Randomised controlled trials (RCT) Systematical reviews (SR) Mini mental State examination (MMSE) Montreal cognitive assessment (MoCA)
类型	Review
语种	英语
国家	South Korea
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000455207400001
WOS关键词	MINI-MENTAL-STATE ; MICROGLIAL ACTIVATION ; OXIDATIVE STRESS ; IMPAIRMENT ; DEMENTIA ; PRETREATMENT ; MEMORY ; RATS
WOS类目	Integrative & Complementary Medicine
WOS研究方向	Integrative & Complementary Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/214682
作者单位	1.Daejeon Univ, Dept Oriental Neuropsychiat, Coll Korean Med, Coll Oriental Med, Daejeon, South Korea; 2.Daejeon Univ, Clin Trial Ctr, Dunsan Korean Med Hosp, Daejeon, South Korea; 3.DaeJeon Univ, Dept Acupuncture & Moxibust, Coll Oriental Med, Daejeon, South Korea; 4.DaeJeon Univ, Coll Oriental Med, Dept Circulatory Internal Med, Daejeon, South Korea
推荐引用方式 GB/T 7714	Kim, Hwan,Kim, Hong Kyoung,Kim, Si Yeon,et al. Cognitive improvement effects of electro-acupuncture for the treatment of MCI compared with Western medications: a systematic review and Meta-analysis[J],2019,19.
APA	Kim, Hwan,Kim, Hong Kyoung,Kim, Si Yeon,Kim, Young Il,Yoo, Ho Ryong,&Jung, In Chul.(2019).Cognitive improvement effects of electro-acupuncture for the treatment of MCI compared with Western medications: a systematic review and Meta-analysis.BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE,19.
MLA	Kim, Hwan,et al."Cognitive improvement effects of electro-acupuncture for the treatment of MCI compared with Western medications: a systematic review and Meta-analysis".BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE 19(2019).