干旱区生态环境知识资源中心(Arid): PCAT-1: A pivotal oncogenic long non-coding RNA in human cancers

Arid

DOI	10.1016/j.biopha.2018.12.014
	PCAT-1: A pivotal oncogenic long non-coding RNA in human cancers
	Yang, Zhi 1; Zhao, Shan 2; Zhou, Xiangyu 1; Zhao, Haiying 1; Jiang, Xiaofeng 1
通讯作者	Zhao, Haiying ; Jiang, Xiaofeng
来源期刊	BIOMEDICINE & PHARMACOTHERAPY
ISSN	0753-3322
EISSN	1950-6007
出版年	2019
卷号	110 页码:493-499
英文摘要	Prostate cancer-associated transcript 1 (PCAT-1) is a newly identified long non-coding RNA comprising two exons, located in the Chr8q24 gene desert approximately 725 kb upstream of the MYC oncogene. PCAT-1 is dysregulated and acts as an oncogene in different types of cancers and has been implicated in several processes correlated with carcinogenesis, such as cell proliferation, invasion, metastasis, apoptosis, cell cycle, chemoresistance, and homologous recombination. The mechanisms underlying the effects of PCAT-1 are complex and involve multiple factors and signaling pathways. In this paper, we systematically review the multiple pathological functions of PCAT-1 in diverse malignancies to elucidate its potential molecular mechanisms and to provide new directions for future research.
英文关键词	Long non-coding RNA PCAT-1 Cancer Oncogene Prognosis
类型	Review
语种	英语
国家	Peoples R China
开放获取类型	gold
收录类别	SCI-E
WOS记录号	WOS:000454879800052
WOS关键词	EXPRESSION PROMOTES PROLIFERATION ; GENOME-WIDE ASSOCIATION ; POOR-PROGNOSIS ; LNCRNA PCAT1 ; HOMOLOGOUS RECOMBINATION ; CELL-PROLIFERATION ; BREAST-CANCER ; GROWTH ARREST ; UP-REGULATION ; MYC
WOS类目	Medicine, Research & Experimental ; Pharmacology & Pharmacy
WOS研究方向	Research & Experimental Medicine ; Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/214658
作者单位	1.China Med Univ, Dept Gen Surg, Affiliated Hosp 4, Chongshan East Rd 4, Shenyang 110032, Liaoning, Peoples R China; 2.China Med Univ, Dept Rheumatol & Immunol, Affiliated Hosp 1, Shenyang, Liaoning, Peoples R China
推荐引用方式 GB/T 7714	Yang, Zhi,Zhao, Shan,Zhou, Xiangyu,et al. PCAT-1: A pivotal oncogenic long non-coding RNA in human cancers[J],2019,110:493-499.
APA	Yang, Zhi,Zhao, Shan,Zhou, Xiangyu,Zhao, Haiying,&Jiang, Xiaofeng.(2019).PCAT-1: A pivotal oncogenic long non-coding RNA in human cancers.BIOMEDICINE & PHARMACOTHERAPY,110,493-499.
MLA	Yang, Zhi,et al."PCAT-1: A pivotal oncogenic long non-coding RNA in human cancers".BIOMEDICINE & PHARMACOTHERAPY 110(2019):493-499.