干旱区生态环境知识资源中心(Arid): Solid-phase extraction coupled with switchable hydrophilicity solvent-based homogeneous liquid-liquid microextraction for chloramphenicol enrichment in environmental water samples: a novel alternative to classical extraction techniques

Arid

DOI	10.1007/s00216-018-1486-8
	Solid-phase extraction coupled with switchable hydrophilicity solvent-based homogeneous liquid-liquid microextraction for chloramphenicol enrichment in environmental water samples: a novel alternative to classical extraction techniques
	Di, Xin; Wang, Xin; Liu, Youping; Guo, Xingjie; Di, Xin
通讯作者	Guo, Xingjie ; Di, Xin
来源期刊	ANALYTICAL AND BIOANALYTICAL CHEMISTRY
ISSN	1618-2642
EISSN	1618-2650
出版年	2019
卷号	411 期号:4 页码:803-812
英文摘要	A simple and efficient method combining solid-phase extraction (SPE) with homogeneous liquid-liquid microextraction (HLLME) has been developed for fast pretreatment of chloramphenicol (CAP) from water samples prior to determination by high-performance liquid chromatography-ultraviolet detection. Oasis HLB sorbent was chosen for SPE. In HLLME, N,N-dimethylcyclohexylamine was used as a CO2-triggered switchable solvent that could switch reversibly between hydrophilic and hydrophobic forms. The parameters influencing both SPE and HLLME were investigated and optimized. Under the optimal conditions, the method exhibited low limit of detection (0.1 ng/mL), good linearity (0.5-50 ng/mL), acceptable precision (RSD <5.0%) and accuracy (RE <4.0%). An enrichment factor of 340 was obtained. The proposed method is simple, fast, cost-effective, and suitable for the determination of trace chloramphenicol in water matrices.
英文关键词	Solid-phase extraction Homogeneous liquid-liquid microextraction Switchable hydrophilicity solvent Chloramphenicol
类型	Article
语种	英语
国家	Peoples R China
收录类别	SCI-E
WOS记录号	WOS:000456132900002
WOS关键词	CHROMATOGRAPHY ; ANTIBIOTICS ; RESISTANCE ; SEPARATION ; TOXICITY ; MILK
WOS类目	Biochemical Research Methods ; Chemistry, Analytical
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/214142
作者单位	Shenyang Pharmaceut Univ, Sch Pharm, POB 54,103 Wenhua Rd, Shenyang 110016, Liaoning, Peoples R China
推荐引用方式 GB/T 7714	Di, Xin,Wang, Xin,Liu, Youping,et al. Solid-phase extraction coupled with switchable hydrophilicity solvent-based homogeneous liquid-liquid microextraction for chloramphenicol enrichment in environmental water samples: a novel alternative to classical extraction techniques[J],2019,411(4):803-812.
APA	Di, Xin,Wang, Xin,Liu, Youping,Guo, Xingjie,&Di, Xin.(2019).Solid-phase extraction coupled with switchable hydrophilicity solvent-based homogeneous liquid-liquid microextraction for chloramphenicol enrichment in environmental water samples: a novel alternative to classical extraction techniques.ANALYTICAL AND BIOANALYTICAL CHEMISTRY,411(4),803-812.
MLA	Di, Xin,et al."Solid-phase extraction coupled with switchable hydrophilicity solvent-based homogeneous liquid-liquid microextraction for chloramphenicol enrichment in environmental water samples: a novel alternative to classical extraction techniques".ANALYTICAL AND BIOANALYTICAL CHEMISTRY 411.4(2019):803-812.