干旱区生态环境知识资源中心(Arid): The diversity and commonalities of the radiation-resistance mechanisms of Deinococcus and its up-to-date applications

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DOI	10.1186/s13568-019-0862-x
	The diversity and commonalities of the radiation-resistance mechanisms of Deinococcus and its up-to-date applications
	Jin, Mengmeng 1; Xiao, Anqi 3; Zhu, Liying 3; Zhang, Zhidong 4; Huang, He 5; Jiang, Ling 2
通讯作者	Zhu, Liying ; Jiang, Ling
来源期刊	AMB EXPRESS
ISSN	2191-0855
出版年	2019
卷号	9 期号:1
英文摘要	Deinococcus is an extremophilic microorganism found in a wide range of habitats, including hot springs, radiation-contaminated areas, Antarctic soils, deserts, etc., and shows some of the highest levels of resistance to ionizing radiation known in nature. The highly efficient radiation-protection mechanisms of Deinococcus depend on a combination of passive and active defense mechanisms, including self-repair of DNA damage (homologous recombination, MMR, ER and ESDSA), efficient cellular damage clearance mechanisms (hydrolysis of damaged proteins, overexpression of repair proteins, etc.), and effective clearance of reactive oxygen species (ROS). Due to these mechanisms, Deinococcus cells are highly resistant to oxidation, radiation and desiccation, which makes them potential chassis cells for wide applications in many fields. This article summarizes the latest research on the radiation-resistance mechanisms of Deinococcus and prospects its biotechnological application potentials.
英文关键词	Deinococcus Ionizing radiation DNA repair Anti-oxidation
类型	Review
语种	英语
国家	Peoples R China
开放获取类型	Green Published, gold
收录类别	SCI-E
WOS记录号	WOS:000483746200001
WOS关键词	RADIODURANS R1 ; SACCHAROMYCES-CEREVISIAE ; TREHALOSE SYNTHASE ; ESCHERICHIA-COLI ; HEAVY-METALS ; EFFICIENT PRODUCTION ; STRESS RESISTANCE ; BIOSORPTION ; EXPRESSION ; PROTEIN
WOS类目	Biotechnology & Applied Microbiology
WOS研究方向	Biotechnology & Applied Microbiology
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/214113
作者单位	1.Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, Nanjing 210019, Jiangsu, Peoples R China; 2.Nanjing Tech Univ, Coll Food Sci & Light Ind, Nanjing 210009, Jiangsu, Peoples R China; 3.Nanjing Tech Univ, Coll Chem & Mol Engn, Nanjing 210009, Jiangsu, Peoples R China; 4.Xinjiang Acad Agr Sci, Inst Microbiol, Urumqi, Xinjiang Uigur, Peoples R China; 5.Nanjing Tech Univ, Coll Pharmaceut Sci, Nanjing 210009, Jiangsu, Peoples R China
推荐引用方式 GB/T 7714	Jin, Mengmeng,Xiao, Anqi,Zhu, Liying,et al. The diversity and commonalities of the radiation-resistance mechanisms of Deinococcus and its up-to-date applications[J],2019,9(1).
APA	Jin, Mengmeng,Xiao, Anqi,Zhu, Liying,Zhang, Zhidong,Huang, He,&Jiang, Ling.(2019).The diversity and commonalities of the radiation-resistance mechanisms of Deinococcus and its up-to-date applications.AMB EXPRESS,9(1).
MLA	Jin, Mengmeng,et al."The diversity and commonalities of the radiation-resistance mechanisms of Deinococcus and its up-to-date applications".AMB EXPRESS 9.1(2019).