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Understanding salinity-fertilizer relationship is of considerable economic importance. Salinity is one of the abiotic stresses limiting crop productivity, especially in arid and semi-arid regions. This study was done to determine whether the nitrogen (N) could alleviate the negative effects of NaCl on several physiological attributes and antioxidative defense system. The results showed that high salinity significantly reduced chlorophyll content (SPAD reading), photosynthesis, stomatal conductance, protein content, and SOD. Moreover, salt treatment increased the activity of CAT and POD. Nitrogen application had significant effects on all the physiological parameters by enhancing chlorophyll content, photosynthesis, protein content, SOD, POD, and CAT. All parameters were significantly affected by the interaction between variety and nitrogen except CAT. The interactive effect between variety and salinity was significant for protein content, SOD, and CAT. The content of protein and the activities of SOD, POD, and CAT were significantly affected by the interaction between nitrogen and salinity. In this study, the application of nitrogen fertilizer was successful in alleviating the adverse effects of salinity. Of all the nitrogen levels used in this study, 210 kg(-1)ha was most effective on most of the measured parameters. The results of this study will be helpful in getting increasing yield by choosing suitable varieties and nitrogen management on saline soils.