Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1111/mec.14778 |
An association between differential expression and genetic divergence in the Patagonian olive mouse (Abrothrix olivacea) | |
Giorello, Facundo M.1,2; Feijoo, Matias1; D’Elia, Guillermo3; Naya, Daniel E.1; Valdez, Lourdes3; Opazo, Juan C.3; Lessa, Enrique P.1 | |
通讯作者 | Giorello, Facundo M. |
来源期刊 | MOLECULAR ECOLOGY
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ISSN | 0962-1083 |
EISSN | 1365-294X |
出版年 | 2018 |
卷号 | 27期号:16页码:3274-3286 |
英文摘要 | Recent molecular studies have found striking differences between desert-adapted species and model mammals regarding water conservation. In particular, aquaporin 4, a classical gene involved in water regulation of model species, is absent or not expressed in the kidneys of desert-adapted species. To further understand the molecular response to water availability, we studied the Patagonian olive mouse Abrothrix olivacea, a species with an unusually broad ecological tolerance that exhibits a great urine concentration capability. The species is able to occupy both the arid Patagonian steppe and the Valdivian and Magellanic forests. We sampled 95 olive mouse specimens from four localities (two in the steppe and two in the forests) and analysed both phenotypic variables and transcriptomic data to investigate the response of this species to the contrasting environmental conditions. The relative size of the kidney and the ratio of urine to plasma concentrations were, as expected, negatively correlated with annual rainfall. Expression analyses uncovered nearly 3,000 genes that were differentially expressed between steppe and forest samples and indicated that this species resorts to the classical gene pathways for water regulation. Differential expression across biomes also involves genes that involved in immune and detoxification functions. Overall, genes that were differentially expressed showed a slight tendency to be more divergent and to display an excess of intermediate allele frequencies, relative to the remaining loci. Our results indicate that both differential expression in pathways involved in water conservation and geographical allelic variation are important in the occupation of contrasting habitats by the Patagonian olive mouse. |
英文关键词 | adaptation detoxification kidney trancriptomics mammals population genomics |
类型 | Article |
语种 | 英语 |
国家 | Uruguay ; Chile |
收录类别 | SCI-E |
WOS记录号 | WOS:000442219600007 |
WOS关键词 | RENIN-ANGIOTENSIN SYSTEM ; GENERALIST WOODRAT HERBIVORES ; PLANT SECONDARY COMPOUNDS ; XENOBIOTIC METABOLISM ; PURIFYING SELECTION ; HETEROMYID RODENTS ; NATURAL-SELECTION ; KIDNEY ; MODEL ; OSMOREGULATION |
WOS类目 | Biochemistry & Molecular Biology ; Ecology ; Evolutionary Biology |
WOS研究方向 | Biochemistry & Molecular Biology ; Environmental Sciences & Ecology ; Evolutionary Biology |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/211709 |
作者单位 | 1.Univ Republica, Dept Ecol & Evoluc, Fac Ciencias, Igua 4225, Montevideo 11400, Uruguay; 2.Univ Republ, Espacio Biol Vegetal Noreste, Ctr Univ Tacuarembo, Tacuarembo, Uruguay; 3.Univ Austral Chile, Inst Ciencias Ambientales & Evolut, Valdivia, Chile |
推荐引用方式 GB/T 7714 | Giorello, Facundo M.,Feijoo, Matias,D’Elia, Guillermo,et al. An association between differential expression and genetic divergence in the Patagonian olive mouse (Abrothrix olivacea)[J],2018,27(16):3274-3286. |
APA | Giorello, Facundo M..,Feijoo, Matias.,D’Elia, Guillermo.,Naya, Daniel E..,Valdez, Lourdes.,...&Lessa, Enrique P..(2018).An association between differential expression and genetic divergence in the Patagonian olive mouse (Abrothrix olivacea).MOLECULAR ECOLOGY,27(16),3274-3286. |
MLA | Giorello, Facundo M.,et al."An association between differential expression and genetic divergence in the Patagonian olive mouse (Abrothrix olivacea)".MOLECULAR ECOLOGY 27.16(2018):3274-3286. |
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