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The lacustrine sediments are one of the best sources to provide information on climate change, specially in peri-glacial climatic region. Schirmacher Oasis, located on the Princess Astrid Coast in Queen Maud Land, is one of the few areas in East Antarctica that provides valuable information on paleoclimate of the region with various depositional features formed due to deglaciation process. This Oasis is dotted with more than 100 lakes of proglacial, land-locked and epi-shelf type. The multi-proxy sedimentological data, generated from the sediment cores from land-locked lakes and grab sample from a proglacial lake, lying in the same drainage line in the central part of Schirmacher region has provided better insight into the paleoclimatic evolution of the region. The immature and chemically unaltered lake sediments have shown restricted drainage pattern. Different phases of warmer and cooler intervals are highlighted by the patterns of fluctuations in different sedimentological and statistical parameters. The dominance of glacial signatures is very clear on the lake sediments as revealed by the surface textures of quartz grains. Physical weathering has mainly controlled the overall sediments and the composition of clay fraction. The clay minerals indicate a gradual shift in the weathering regime and therewith in climate from strongly glacial to fluvioglacial specially around 42 ka. This indicates beginning of warming of the area much before the LGM. But the warm period is not strong enough to alter the overall clay chemistry. Proxy records indicate short-period climatic oscillations during late Quaternary.