Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1167/iovs.18-25418 |
Retinal Nerve Fiber Layer Thickness in Children: The Gobi Desert Children Eye Study | |
Wang, Chun-Yan1; Zheng, Yan-Fei1; Liu, Bin1; Meng, Zi-Wei1; Hong, Fei1; Wang, Xiao-xia1; Wang, Xiao-Juan1; Du, Lagan1; Wang, Ian Y.2; Zhu, Dan1; Tao, Yong3; You, Qi Sheng4; Jonas, Jost B.4,5 | |
通讯作者 | Zhu, Dan ; You, Qi Sheng |
来源期刊 | INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE |
ISSN | 0146-0404 |
EISSN | 1552-5783 |
出版年 | 2018 |
卷号 | 59期号:12页码:5285-5291 |
英文摘要 | PURPOSE. Because there is a paucity of population-based data on retinal nerve fiber layer thickness (RNFLT) for children, we measured the RNFLT and its associations in schoolchildren. METHODS. The population-based Gobi Desert Children Eye Study included all schoolchildren aged 6 to 21 years living in Ejina, Inner Mongolia. The children underwent a comprehensive ocular examination with cycloplegic refractometry and spectral-domain optical coherence tomography of the optic nerve head. The peripapillary RNFLT was measured on the optical coherence tomography images of a circular scan with a diameter of 3.4 mm. RESULTS. Out of 1565 participants, RNFLT data were available for 1440 (92.5%) children. The mean global RNFLT was 101.3 6 9.2 lm in right eyes. The RNFLT was thickest in the temporal inferior sector (157.3 lm), followed by the temporal superior sector (143.8 lm), the nasal inferior sector (109.7 lm), the nasal superior sector (106.9 lm), temporal sector (85.2 lm), and the nasal sector (61.7 lm). In multivariate analysis, the RNFLT decreased with higher myopic refractive error (P < 0.001), male sex (P = 0.001), higher intraocular pressure (P = 0.002), and lower birth weight (P = 0.03). It was not significantly associated with age (P = 0.19), body mass index (P = 0.57), mean arterial blood pressure (P = 0.33), pulse rate (P = 0.28), and subfoveal choroidal thickness (P = 0.11). CONCLUSIONS. The RNFLT in children showed a regional distribution, with the thickest part in the temporal inferior sector and the thinnest part located in the nasal sector. The overall RNLFT significantly decreased with higher myopic refractive error and male sex. In schoolchildren, in contrast to adults, the RNFLT did not decrease with older age. These findings may be considered when interpreting RNFLT data in children. |
英文关键词 | retinal nerve fiber layer thickness optical coherence tomography optic nerve optic nerve head glaucoma |
类型 | Article |
语种 | 英语 |
国家 | Peoples R China ; Germany |
收录类别 | SCI-E |
WOS记录号 | WOS:000449417000028 |
WOS关键词 | OPTICAL COHERENCE TOMOGRAPHY ; BEIJING EYE ; GLAUCOMA ; PROGRESSION ; AGE ; POPULATION ; DEFECTS ; RATES |
WOS类目 | Ophthalmology |
WOS研究方向 | Ophthalmology |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/210315 |
作者单位 | 1.Inner Mongolia Med Univ, Affiliated Hosp, 1 Tongdaobei St, Hohhot 010050, Inner Mongolia, Peoples R China; 2.Univ Hong Kong, Dept Ophthalmol, Hong Kong, Hong Kong, Peoples R China; 3.Capital Med Univ, Beijing Chaoyang Hosp, Dept Ophthalmol, Beijing, Peoples R China; 4.Capital Med Univ, Beijing Tongren Hosp, Beiling Inst Ophthalmol, Beijing Ophthalmol & Visual Sci Key Lab, Beijing, Peoples R China; 5.Heidelberg Univ, Dept Ophthalmol, Med Fac Mannheim, Mannheim, Germany |
推荐引用方式 GB/T 7714 | Wang, Chun-Yan,Zheng, Yan-Fei,Liu, Bin,et al. Retinal Nerve Fiber Layer Thickness in Children: The Gobi Desert Children Eye Study[J],2018,59(12):5285-5291. |
APA | Wang, Chun-Yan.,Zheng, Yan-Fei.,Liu, Bin.,Meng, Zi-Wei.,Hong, Fei.,...&Jonas, Jost B..(2018).Retinal Nerve Fiber Layer Thickness in Children: The Gobi Desert Children Eye Study.INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,59(12),5285-5291. |
MLA | Wang, Chun-Yan,et al."Retinal Nerve Fiber Layer Thickness in Children: The Gobi Desert Children Eye Study".INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 59.12(2018):5285-5291. |
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