Arid
DOI10.1016/j.indcrop.2018.02.064
Artemisia herba-alba Asso. essential oil antibacterial activity and acute toxicity
Bertella, Anis1; Benlahcen, Kheira1; Abouamama, Sidaoui1; Pinto, Diana C. G. A.2; Maamar, Karim1; Kihal, Mebrouk1; Silva, Artur M. S.2
通讯作者Bertella, Anis ; Silva, Artur M. S.
来源期刊INDUSTRIAL CROPS AND PRODUCTS
ISSN0926-6690
EISSN1872-633X
出版年2018
卷号116页码:137-143
英文摘要

Artemisia herba-alba Asso., known as the desert wormwood, is a medicinal plant and its essential oil is used in Algerian herbal medicine. In the present study the in vitro antibacterial activity against 21 bacterial strains and chemical composition of Artemisia herba-alba essential oil were investigated. The acute toxicity by determination of the median lethal dose was also studied. The results of gas chromatography/mass spectrometry analysis of the essential oil gave 19 compounds accounting for 98.7% and the major constituent was camphor with an amount of 50.7%. A significant antibacterial effect was observed with important zones of inhibition against Klebsiella oxytoca (31.3 mm) by disc diffusion method and against Acinetobacter baumannnii (47.6 mm) by microatmoshphere method. The minimum inhibitory concentration and the minimum bactericidal concentration values were ranging from 5 to 10 mg mL(-1) and 10-20 mg mL(-1), respectively. Moreover, their ratio exhibited by the essential oil was 2. The bactericidal end point was achieved after 24 h of exposure to the essential oil, for all the bacteria assayed. The oil was slightly toxic with a median lethal dose of 615 mg kg (similar to 1). The results of this study suggest that the essential oil of Artemisia herba-alba can be a source of natural antibacterial agents with potential pharmacological applications.


英文关键词Artemisia herba-alba Asso. Essential oil Antibacterial activity Median lethal dose Camphor
类型Article
语种英语
国家Algeria ; Portugal
收录类别SCI-E
WOS记录号WOS:000429506000016
WOS关键词CHEMICAL-COMPOSITION ; ANTIMICROBIAL PROPERTIES ; MODE
WOS类目Agricultural Engineering ; Agronomy
WOS研究方向Agriculture
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/210038
作者单位1.Univ Oran 1 Ahmed BenBella, Fac Life & Nat Sci, Dept Biol, Lab Appl Microbiol, Oran, Algeria;
2.Univ Aveiro, Dept Chem & Organ Chem, Nat Prod & Food Stuffs QOPNA, Campus Santiago, P-3810193 Aveiro, Portugal
推荐引用方式
GB/T 7714
Bertella, Anis,Benlahcen, Kheira,Abouamama, Sidaoui,et al. Artemisia herba-alba Asso. essential oil antibacterial activity and acute toxicity[J],2018,116:137-143.
APA Bertella, Anis.,Benlahcen, Kheira.,Abouamama, Sidaoui.,Pinto, Diana C. G. A..,Maamar, Karim.,...&Silva, Artur M. S..(2018).Artemisia herba-alba Asso. essential oil antibacterial activity and acute toxicity.INDUSTRIAL CROPS AND PRODUCTS,116,137-143.
MLA Bertella, Anis,et al."Artemisia herba-alba Asso. essential oil antibacterial activity and acute toxicity".INDUSTRIAL CROPS AND PRODUCTS 116(2018):137-143.
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