Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1186/s13059-018-1393-5 |
The peopling of the last Green Sahara revealed by high-coverage resequencing of trans-Saharan patrilineages | |
D’Atanasio, Eugenia1,2; Trombetta, Beniamino1; Bonito, Maria1; Finocchio, Andrea3; Di Vito, Genny1; Seghizzi, Mara1; Romano, Rita4; Russo, Gianluca4; Paganotti, Giacomo Maria5,6; Watson, Elizabeth7; Coppa, Alfredo8; Anagnostou, Paolo8,9; Dugoujon, Jean-Michel10; Moral, Pedro11; Sellitto, Daniele12; Novelletto, Andrea3; Cruciani, Fulvio1,12 | |
通讯作者 | Cruciani, Fulvio |
来源期刊 | GENOME BIOLOGY
![]() |
ISSN | 1474-760X |
出版年 | 2018 |
卷号 | 19 |
英文摘要 | Background: Little is known about the peopling of the Sahara during the Holocene climatic optimum, when the desert was replaced by a fertile environment. Results: In order to investigate the role of the last Green Sahara in the peopling of Africa, we deep-sequence the whole non-repetitive portion of the Y chromosome in 104 males selected as representative of haplogroups which are currently found to the north and to the south of the Sahara. We identify 5,966 mutations, from which we extract 142 informative markers then genotyped in about 8,000 subjects from 145 African, Eurasian and African American populations. We find that the coalescence age of the trans-Saharan haplogroups dates back to the last Green Sahara, while most northern African or sub-Saharan clades expanded locally in the subsequent arid phase. Conclusions: Our findings suggest that the Green Sahara promoted human movements and demographic expansions, possibly linked to the adoption of pastoralism. Comparing our results with previously reported genome-wide data, we also find evidence for a sex-biased sub-Saharan contribution to northern Africans, suggesting that historical events such as the trans-Saharan slave trade mainly contributed to the mtDNA and autosomal gene pool, whereas the northern African paternal gene pool was mainly shaped by more ancient events. |
英文关键词 | MSY Target next generation sequencing Green Sahara Trans-Saharan haplogroups |
类型 | Article |
语种 | 英语 |
国家 | Italy ; Botswana ; USA ; Sweden ; France ; Spain |
收录类别 | SCI-E |
WOS记录号 | WOS:000425109700001 |
WOS关键词 | HUMAN Y-CHROMOSOME ; HIGH-RESOLUTION ANALYSIS ; SEGMENTAL DUPLICATIONS ; GENETIC LANDSCAPE ; MIGRATORY EVENTS ; MTDNA VARIATION ; HAPLOGROUP-E ; AFRICA ; SEQUENCE ; EXPANSION |
WOS类目 | Biotechnology & Applied Microbiology ; Genetics & Heredity |
WOS研究方向 | Biotechnology & Applied Microbiology ; Genetics & Heredity |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/209530 |
作者单位 | 1.Sapienza Univ Roma, Dipartimento Biol & Biotecnol C Darwin, Rome, Italy; 2.Sapienza Univ Roma, Fdn Cenci Bolognetti, Ist Pasteur, Rome, Italy; 3.Univ Roma Tor Vergata, Dipartimento Biol, Rome, Italy; 4.Sapienza Univ Roma, Dipartimento Sanita Pubbl & Malattie Infett, Rome, Italy; 5.Botswana Univ Pennsylvania Partnership, Gaborone, Botswana; 6.Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA; 7.Swedish Museum Nat Hist, Stockholm, Sweden; 8.Sapienza Univ Roma, Dipartimento Biol Ambientale, Rome, Italy; 9.Ist Italiano Antropol, Rome, Italy; 10.Univ Toulouse 3 Paul Sabatier, CNRS, Toulouse, France; 11.Univ Barcelona, Dept Anim Biol Anthropol, Biodivers Res Inst, Barcelona, Spain; 12.CNR, Ist Biol & Patol Mol, Rome, Italy |
推荐引用方式 GB/T 7714 | D’Atanasio, Eugenia,Trombetta, Beniamino,Bonito, Maria,et al. The peopling of the last Green Sahara revealed by high-coverage resequencing of trans-Saharan patrilineages[J],2018,19. |
APA | D’Atanasio, Eugenia.,Trombetta, Beniamino.,Bonito, Maria.,Finocchio, Andrea.,Di Vito, Genny.,...&Cruciani, Fulvio.(2018).The peopling of the last Green Sahara revealed by high-coverage resequencing of trans-Saharan patrilineages.GENOME BIOLOGY,19. |
MLA | D’Atanasio, Eugenia,et al."The peopling of the last Green Sahara revealed by high-coverage resequencing of trans-Saharan patrilineages".GENOME BIOLOGY 19(2018). |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。