Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1002/ecs2.2427 |
An ecoimmunological approach to disease in tortoises reveals the importance of lymphocytes | |
Sandmeier, Franziska C.1; Weitzman, Chava L.2; Tracy, C. Richard2 | |
通讯作者 | Sandmeier, Franziska C. |
来源期刊 | ECOSPHERE
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ISSN | 2150-8925 |
出版年 | 2018 |
卷号 | 9期号:9 |
英文摘要 | We quantified the severity of upper respiratory tract disease (URTD) and immunological metrics (differential white blood cell counts and bacteria-killing ability of blood plasma) in relation to climatic variables in 20 populations of Mojave desert tortoise (Gopherus agassizii). Prevalence and infection intensity of Mycoplasma agassizii, an etiological agent of URTD, have previously been quantified for these populations (Weitzman et al. 2017). Immunological variables were reduced by principal component analyses and separated into cells involved in inflammation (PC1) and cellular functions mediated by lymphocytes and basophils (PC2). In population-level models, the mean number of lymphocytes per individual was associated with mean annual number of days below freezing. Lymphocytes were also positively associated with mean infection intensity of M. agassizii. Additionally, prevalence of URTD was closely associated with PC1 (cells associated with inflammation). This suggests that at least two immunological strategies are involved in responding to M.agassizii, one that involves primarily lymphocytes and one that involves inflammatory mechanisms. Recent studies on immunology in Testudines suggest that a large proportion of lymphocytes in this taxon are similar to B-1 lymphocytes of mammals and have phagocytic properties. Controlled experiments are needed to understand the disease mitigation of these lymphocytes in desert tortoises. |
英文关键词 | chronic disease ectotherm inflammation phagocytosis reptile temperature |
类型 | Article |
语种 | 英语 |
国家 | USA |
收录类别 | SCI-E |
WOS记录号 | WOS:000446834100031 |
WOS关键词 | RESPIRATORY-TRACT DISEASE ; MYCOPLASMA-AGASSIZII ; GOPHERUS-AGASSIZII ; B-CELLS ; DESERT ; ANTIBODIES ; PATTERNS |
WOS类目 | Ecology |
WOS研究方向 | Environmental Sciences & Ecology |
来源机构 | Colorado State University |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/208850 |
作者单位 | 1.Colorado State Univ Pueblo, Biol Dept, 2200 Bonforte Blvd, Pueblo, CO 81001 USA; 2.Univ Nevada, Dept Biol, Program Ecol Evolut & Conservat Biol, 1664 N Virginia St, Reno, NV 89557 USA |
推荐引用方式 GB/T 7714 | Sandmeier, Franziska C.,Weitzman, Chava L.,Tracy, C. Richard. An ecoimmunological approach to disease in tortoises reveals the importance of lymphocytes[J]. Colorado State University,2018,9(9). |
APA | Sandmeier, Franziska C.,Weitzman, Chava L.,&Tracy, C. Richard.(2018).An ecoimmunological approach to disease in tortoises reveals the importance of lymphocytes.ECOSPHERE,9(9). |
MLA | Sandmeier, Franziska C.,et al."An ecoimmunological approach to disease in tortoises reveals the importance of lymphocytes".ECOSPHERE 9.9(2018). |
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