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The late Quaternary sequences of north-eastern Algeria composed of alternating dark and light layers, which are rich in molluscan fauna, could correspond to synchronous environmental phases. The facies variations of the Morsott Region deposits were systematically sampled as part of a sedimentological and malacological study in order to establish a palaeoenvironmental and climatic reconstruction of the late Quaternary. The alternation of sandy clayey silts levels, which contain abundant molluscan hygrophilous organisms, indicates an isostasis cycle followed, at the top, by a succession of rhexistasis and biostasis cycles. The molluscan record shows a dominant succession of xerophilous organisms in relation to the hygrophilous organisms. The faunistic richness in the fine levels is linked to sub-humid periods where the region has suffered numerous floods. The reduction in the number of species in the coarse levels comes is likely due to desiccation when the climate was semi-arid. This study is new in Algeria and will provide an insight into climatic changes. Further research will be required in order to understand the fluvial dynamics during the Quaternary.