Arid
DOI10.1002/ajim.22816
Impulse oscillometry measurement of distal airways obstruction in depleted uranium-exposed Gulf War veterans
Hines, Stella E.1,2,3; Barnes, Ashley H.4; Brown, Clayton5; Gucer, Patricia1,2; Oliver, Marc S.1,2; Gaitens, Joanna M.1,2; Condon, Marian1,2; McDiarmid, Melissa1,2
通讯作者Hines, Stella E.
来源期刊AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
ISSN0271-3586
EISSN1097-0274
出版年2018
卷号61期号:4页码:308-316
英文摘要

IntroductionA cohort of Gulf War I veterans who sustained exposure to depleted uranium undergoes biennial surveillance for potential uranium-related health effects. We performed impulse oscillometry and hypothesized that veterans with higher uranium body burdens would have more obstructive abnormalities than those with lower burdens.


MethodsWe compared pulmonary function of veterans in high versus low urine uranium groups by evaluating spirometry and oscillometry values.


ResultsOverall mean spirometry and oscillometry resistance values fell within the normal ranges. There were no significant differences between the high and low uranium groups for any parameters. However, more veterans were classified as having obstruction by oscillometry (42%) than spirometry (8%).


ConclusionsWhile oscillometry identified more veterans as obstructed, obstruction was not uranium-related. However, the added sensitivity of this method implies a benefit in wider surveillance of exposed cohorts and holds promise in identifying abnormalities in areas of the lung historically described as silent.


英文关键词depleted uranium desert storm distal airways gulf war impulse oscillometry spirometry veterans
类型Article
语种英语
国家USA
收录类别SCI-E
WOS记录号WOS:000427561700004
WOS关键词COHORT ; HEALTH
WOS类目Public, Environmental & Occupational Health
WOS研究方向Public, Environmental & Occupational Health
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/207493
作者单位1.Dept Vet Affairs Med Ctr, Baltimore, MD USA;
2.Univ Maryland, Sch Med, Dept Med, Div Occupat & Environm Med, 11 S Paca St,Second Floor, Baltimore, MD 21201 USA;
3.Univ Maryland, Sch Med, Dept Med, Div Pulm & Crit Care Med, 11 S Paca St,Second Floor, Baltimore, MD 21201 USA;
4.Univ Maryland, Sch Med, Baltimore, MD 21201 USA;
5.Univ Maryland, Sch Med, Dept Epidemiol & Publ Hlth, Baltimore, MD 21201 USA
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GB/T 7714
Hines, Stella E.,Barnes, Ashley H.,Brown, Clayton,et al. Impulse oscillometry measurement of distal airways obstruction in depleted uranium-exposed Gulf War veterans[J],2018,61(4):308-316.
APA Hines, Stella E..,Barnes, Ashley H..,Brown, Clayton.,Gucer, Patricia.,Oliver, Marc S..,...&McDiarmid, Melissa.(2018).Impulse oscillometry measurement of distal airways obstruction in depleted uranium-exposed Gulf War veterans.AMERICAN JOURNAL OF INDUSTRIAL MEDICINE,61(4),308-316.
MLA Hines, Stella E.,et al."Impulse oscillometry measurement of distal airways obstruction in depleted uranium-exposed Gulf War veterans".AMERICAN JOURNAL OF INDUSTRIAL MEDICINE 61.4(2018):308-316.
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