干旱区生态环境知识资源中心(Arid): 药物联合治疗慢性前列腺炎临床疗效观察

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	药物联合治疗慢性前列腺炎临床疗效观察
其他题名	A clinical survey of combined use of different drugs in the treatment of chronic prostatitis(report of 153 cases)
	陶然 1; 周利群 2; 王刚 2; 肖云羟 2; 潘柏年 2
来源期刊	中华泌尿外科杂志
ISSN	1000-6702
出版年	2003
卷号	24 期号:10 页码:699-701
中文摘要	目的　探讨慢性前列腺炎联合药物治疗的临床疗效。方法　选择中重度慢性前列腺炎153例，其中细菌性前列腺炎20例，非细菌性前列腺炎133例，按照美国国立卫生研究所(NIH)制定的前列腺炎症状评分标准(CPSI)和前列腺按摩液(EPS)指标变化及细菌学检查结果评估疗效。应用敏感抗生素、alpha_1受体阻滞剂、选择性COX－2抑制剂、中成药等联合治疗1.5～5个月，对比分析疗效。结果　153例平均随访11.8个月，行两次CPSI，平均13.4分，与治疗前平均32.6分比较差异有显著性意义(P<0.00001)。依据CPSI进行疗效判定，治愈15.7%,显效49.1%，有效18.8%，无交16.7%，总有效率83.6%；治疗后平均WBC11.6个/HP，与治疗前(32.4个/HP)比较差异有显著性意义(P<0.00001)。20例慢性细菌性前列腺炎患者治疗后两杯判定试验(PPMT)法行细菌培养，14例转为阴性，转阴率70.0%。结论　两杯判定试验对慢性前列腺炎分类简单易行，CPSI是一种较好的疗效评价方法，合适的抗生素、alpha_1受体阻滞剂、选择性COX－2抑制剂和中药等联合应用对慢性前列腺炎有较好的疗效。
英文摘要	Objective To study the efficacy of consecutive drugs in the treatment of chronic prostatitis. Methods 153 oases of moderate & severes chronic prostatids were treated with consecutive drugs with sensitive antibiotics, alpha_1-blocker, inhibitor of cox-2 and traditional Chinese herb,20 cases being chronic bacterial and 133 nonbacterial. They were classified and evaluated according to the CPSI & EPS examinations as analyzed by T test. Results All cases were followed up for an average of 11.8 months (8 ～ 18 months). The average CPSI score was 32. 6 (32. 7 5.3) before treatment and 13. 4 ( 12. 8 7.3) after treatment (P <0. 00001). Based on the study of CPSI, the curative rate was 15.7%, the remarkable effective rate 49. 1%, and the improving rate was 18.8%, the total effective rate being 83. 6% .whereas the noneffective rate was 16.7%. The average "WBC count in EPS after treatment was 11.6(11.6 10.9) and 32.4 (32.4 29.7) before treatment (P < 0.00001). 20 cases of chronic bacterial prostatitis had positive bacte-rial culture of EPS, 14 of which turned negative after treatment and the negative rate being 70. 0%. Conclusions PPMT is a reliable method to diagnose prostatitis,and easy to cany out. NIH-CPSI is an reliable method to evaluate the drug therapy. The consecutive drugs treatment, including the proper antibiotics, alpha_1-blocker, the inhibitor of COX-2 and traditional Chinese herb can be an effective therapy for chronic prostati-tis.
中文关键词	慢性前列腺炎 ; 药物 ; 联合治疗
英文关键词	chronic prostatitis drugs combine treatment
语种	中文
国家	中国
收录类别	CSCD
WOS类目	SURGERY
WOS研究方向	Surgery
CSCD记录号	CSCD:1258321
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/204726
作者单位	1.北京潞河医院泌尿外科, 北京 101149, 中国; 2.北京大学泌尿外科研究所
推荐引用方式 GB/T 7714	陶然,周利群,王刚,等. 药物联合治疗慢性前列腺炎临床疗效观察[J],2003,24(10):699-701.
APA	陶然,周利群,王刚,肖云羟,&潘柏年.(2003).药物联合治疗慢性前列腺炎临床疗效观察.中华泌尿外科杂志,24(10),699-701.
MLA	陶然,et al."药物联合治疗慢性前列腺炎临床疗效观察".中华泌尿外科杂志 24.10(2003):699-701.