干旱区生态环境知识资源中心(Arid): 脊柱恶性纤维组织细胞瘤临床诊治16例报告

Arid

	脊柱恶性纤维组织细胞瘤临床诊治16例报告
其他题名	Clinical diagnosis and treatment of the malignant-fibrous histocytoma in the spine (16 cases report)
	肖建如; 陈华江; 滕红林; 魏海峰; 荆鑫; 陈雄生; 贾连顺
来源期刊	中国脊柱脊髓杂志
ISSN	1004-406X
出版年	2003
卷号	13 期号:8 页码:455-458
中文摘要	目的：探讨脊柱恶性纤维组织细胞瘤的临床特点及其手术方式。方法：1996～2001年收治16例脊柱恶性纤维组织细胞瘤患者（平均年龄47岁），经临床及影像学诊断确诊后采取手术治疗。肿瘤位于预椎者1例，行前路肿瘤切除钢板固定；位于胸椎者6例，采用经胸人路行肿瘤切除、植骨水泥椎体重建、后路椎加Z－plate内固定；位于腰椎者3例，采用后路、侧方入路或胸腹联合入路行肿瘤切除、植骨或骨水泥椎体重建、后路椎弓根、Kaneda等内固定方法；位于骶椎者4例，采用TSRH腰椎骨盆内固定重建术，2例患者仅行肿瘤切除术。术前、术后均进行化疗。术后对患者疼痛情况、影像学表现等进行随访，平均随访2.5年。结果：术中平均出血量2306ml，所有患者平均疼痛下降2.19级，7例有肿瘤复发（43.75%），未发现椎体塌陷和内固定失败。随访中全组均存活。结论：在胸腹腔等部位生长的肿瘤容易形成巨大软组织肿块，术中出血较多。根据肿瘤的不同部位，在肿瘤切除后，可以采用不同型式的椎体重建和内固定。术前术后应用联合化疗。
英文摘要	Objective: To study the clinical features and the operative methods of the malignant-fibrous histocytoma (MFH) in the spine.Method:From Jan,1996 to Dec,2001,16 oases with MFH(age range,27~6l years old),10 male and 6 female,were admitted to the hospital. After the resection of the tumor lesion. one patient undenvent anterior cervical procedure with anterior cervical plating; six with thoracic lesion underwent transthoracic approach,reeonstructed with bone-grafting or bone cement and internal fixation with Z-plating or Kaneda; 3 with lumbar lesion underwent transpedicular screws fixation or Kaneda rod through posterior.lateral or abdominothoracie approaches.Four with sacral tumors underwent TSRH himbosacral reconstruction. All patients received chemotherapy pre-and post-operativcly. The patients were clinically and radiologically followed up with a mean of 2.5 years. Result: The mean introperativc; bleeding was 2 306 millimeters. The pain scoring decreased 2.19 points on the average. In the total of 16 patients, seven developed recurrence after a mean of two years follow-up. No vertebral collapse and internal fixation failure occurred. None of them died so far as the paper was subscribed. Conclusiom The MHF tends to develop a huge mass of soft tissue in the abdominothoraoic cavity. Intro-operative over-bleeding should be kept in mind by the surgeons. Based on the various approaches of the tumor lesion, the different vertebral reconstruction and internal fixation could be adopted. The pre-and postoperative chemotherapy should be indispensable part of the comprehensive treatment of the MFH.
中文关键词	脊柱 ; 恶性纤维组织细胞瘤 ; 外科治疗
英文关键词	Spine Malignant-fibrous histocytoma Surgical treatment
语种	中文
国家	中国
收录类别	CSCD
WOS类目	ONCOLOGY
WOS研究方向	Oncology
CSCD记录号	CSCD:1254515
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/204601
作者单位	第二军医大学长征医院骨科, 上海 20003, 中国
推荐引用方式 GB/T 7714	肖建如,陈华江,滕红林,等. 脊柱恶性纤维组织细胞瘤临床诊治16例报告[J],2003,13(8):455-458.
APA	肖建如.,陈华江.,滕红林.,魏海峰.,荆鑫.,...&贾连顺.(2003).脊柱恶性纤维组织细胞瘤临床诊治16例报告.中国脊柱脊髓杂志,13(8),455-458.
MLA	肖建如,et al."脊柱恶性纤维组织细胞瘤临床诊治16例报告".中国脊柱脊髓杂志 13.8(2003):455-458.