干旱区生态环境知识资源中心(Arid): 直肠癌局部切除术54例疗效分析

Arid

	直肠癌局部切除术54例疗效分析
其他题名	Local resection for the treatment of low rectal carcinoma: report of 54 patients
	韩少良 1; 花亚伟 1; 姬社青 1; 高阳 1; 王程虎 1; 邵永孚 2
来源期刊	中华普通外科杂志
ISSN	1007-631X
出版年	2002
卷号	17 期号:7 页码:395-397
中文摘要	目的探讨直肠癌局部切除的手术方式及疗效。方法回顾分析1975-2000年间局部切除治疗直肠癌54例的临床资料。结果局部切除术式包括经肛局部切除44例、经骶局部切除6例、经肛门括约肌局部切除２例及经阴道局部切除2例。48例肿瘤直径≤３cm,6例＞３cm。本组高分化腺癌48例，中分化腺癌６例；肿瘤浸润浅肌层（T2）8例。术后１例发生吻合口瘘、2例发生排便障碍，２例发生肠道出血。术手所有病例均接受放疗化疗，随访中2例局部复发（15），复发时间为术后42(10-84)个月，复发病例再次行Miles手术。本组病例5年生存率为85(45/53),10年生存率为55(29/53),包括T1病变者分别为87(39/45)及69(27/39),T2分别为75(6/8)及33(2/6)。结论只要适应症选择得当，局部切除术治疗直肠癌可取得与根治术类似的疗效。
英文摘要	Objective To evaluate outcome of local excision of rectal caneer for curative purpose. Methods Fifty-four patients with low rectal carcinoma undergoing local excision from 1975 to 2000 were analyzed relrospeelively. Results In this study, 44 patients underwent trans-anal resection (TAR), 6 did trans-sacral re-section (TSR), 2 each did trans-sphinclerie, local resection (TSLR) and trans-vaginal resection (TVR). Most tumors were within 8 cm from the anal verge, and the average distance was 6.6 cm in TSR, 5.2 cm in TVR, 4.7 cm in TAR arid 4.5 cm in TSLR, respectively. Most tumors (89%, 48/54) were less than 3 cm in diameter, six tumors (11%) were larger than 3 cm. The mean size of tumor was 3.5 cm in TSR group,3.5 cm in TSLR ,2.5 cm in TAR, and 2.5 cm in TVR. Tumors were in T_1 stage in 46 patients and in T_2 in 8 patients. Postoperative compli-cations included anastomosis leakage in one, sphincteric dysfunction in 2, and anal bleeding in 2. Eight patients (15.1 %) recurred locally during the period of postoperative follow-up, at a mean time of 42.2 months ranging 10 to 84 months. Five, ten-year overall survival rates were 86.7% (39/45) and 69.2% (27/39) for T_1 tumor, and 75.0% (6/8) and 33.3% (2/6) for T_2 tumor, respectively. Conclusions Local excision of rectal cancer is of less injury and early recovery in properly selected patients while not at the expense of long term survival.
中文关键词	结肠直肠肿瘤 ; 局部解剖学 ; 外科手术 ; 治疗
英文关键词	colorectal neoplasms anatomy regional surgical procedures operative
语种	中文
国家	中国
收录类别	CSCD
WOS类目	ONCOLOGY
WOS研究方向	Oncology
CSCD记录号	CSCD:1095619
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/203745
作者单位	1.河南省肿瘤医院普外科, 郑州, 河南 450003, 中国; 2.中国医学科学院肿瘤医院腹部外科
推荐引用方式 GB/T 7714	韩少良,花亚伟,姬社青,等. 直肠癌局部切除术54例疗效分析[J],2002,17(7):395-397.
APA	韩少良,花亚伟,姬社青,高阳,王程虎,&邵永孚.(2002).直肠癌局部切除术54例疗效分析.中华普通外科杂志,17(7),395-397.
MLA	韩少良,et al."直肠癌局部切除术54例疗效分析".中华普通外科杂志 17.7(2002):395-397.